Hematologic Malignancies USMLE Step 1 Practice Questions
55 board-style USMLE Step 1 questions in Hematology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard25. A 63-year-old woman presents with frequent headaches and burning pain with erythema of her hands and feet for 3 months. Vital signs: BP 148/92 mmHg, HR 94/min, RR 16/min, Temp 3…
- USMLE Step 1 · medium26. A 59-year-old man presents with headaches, dizziness, and intense pruritus after hot showers. Vital signs show BP 158/92 mmHg, HR 88/min, RR 16/min, temp 37.2°C. Examination rev…
- USMLE Step 1 · medium27. A 72-year-old man presents with headaches, blurry vision, and recurrent epistaxis. Vital signs show BP 158/92 mmHg, HR 88/min, RR 16/min, temperature 37.2°C, and SpO2 98% on roo…
- USMLE Step 1 · easy28. A 68-year-old man presents with progressive back pain and fatigue. Vital signs: BP 148/92, HR 88, RR 16, Temp 37.2°C, SpO2 98% on room air. Examination reveals vertebral tendern…
- USMLE Step 1 · medium29. A 58-year-old woman presents with a rapidly enlarging, painful left neck mass over one month. Vital signs: BP 128/82, HR 102, RR 18, Temp 37.8°C, SpO2 98%. She denies fever and…
- USMLE Step 1 · medium30. A 63-year-old woman presents with progressive painless generalized lymphadenopathy over 6 months. Vital signs: BP 128/82, HR 88, RR 16, Temp 37.2°C, SpO2 98%. She denies night s…
- USMLE Step 1 · medium31. A 9-year-old boy from equatorial Africa presents with fever (38.5°C), tachycardia (110 bpm), and a rapidly enlarging jaw mass over two weeks. Biopsy shows sheets of medium-sized…
- USMLE Step 1 · medium32. A 24 year old man presents with painless cervical lymphadenopathy, low grade fever, and drenching night sweats. He reports that the nodes become painful after drinking alcohol.…
- USMLE Step 1 · hard33. A 58-year-old man presents with a 3-month history of fatigue and recurrent infections. Vital signs show BP 128/82, HR 98, RR 18, Temp 37.2°C, SpO2 98%. Physical examination reve…
- USMLE Step 1 · medium34. A 71-year-old man presents with asymptomatic lymphocytosis discovered on routine laboratory work. He now reports painless cervical lymphadenopathy on examination. Vital signs ar…
- USMLE Step 1 · medium35. A 52-year-old man presents with progressive fatigue, early satiety, and unintentional 8-lb weight loss over 2 months. Vital signs: BP 138/82, HR 102, RR 18, Temp 37.2°C, SpO2 98…
- USMLE Step 1 · medium36. A 41-year-old woman presents with progressive fatigue, spontaneous gingival bleeding, and easy bruising. Vital signs show BP 118/76, HR 102, RR 18, temperature 37.2°C, SpO2 98%…
- USMLE Step 1 · easy37. A 6-year-old boy presents with three weeks of progressive fatigue, fever, and bilateral leg pain. Vital signs: temperature 38.5°C, heart rate 118/min, blood pressure 95/60 mmHg,…
- USMLE Step 1 · medium38. A 58-year-old woman presents with a rapidly enlarging painless cervical lymph node and drenching night sweats for 3 weeks. Vital signs: BP 128/82, HR 98, RR 18, Temp 38.2°C, SpO…
- USMLE Step 1 · hard39. A 69-year-old man presents with progressive weight loss and painless diffuse lymphadenopathy. Vital signs show BP 138/82, HR 92, RR 18, temperature 37.2°C, SpO2 98%. Laboratory…
- USMLE Step 1 · medium40. A 63-year-old woman presents with 3 months of painless generalized lymphadenopathy, fatigue, and night sweats. Vital signs: BP 128/82, HR 92, RR 18, Temp 37.2°C, SpO2 98%. CBC s…
- USMLE Step 1 · hard41. A 9-year-old boy from equatorial Africa presents with a rapidly enlarging jaw mass and fever. Vital signs show temperature 38.5°C, HR 110/min, BP 105/68 mmHg, RR 22/min, SpO2 98…
- USMLE Step 1 · medium42. A 24-year-old woman comes to the physician because of a painless enlarging mass on the left side of her neck for 2 months. She has had intermittent fevers and night sweats. Exci…
- USMLE Step 1 · hard43. A 72-year-old man presents with severe headaches, blurry vision, and spontaneous epistaxis. Vital signs show BP 168/94 mmHg, HR 88/min, RR 16/min, temp 37°C. Fundoscopy reveals…
- USMLE Step 1 · medium44. A 68-year-old woman presents with progressive fatigue. Vital signs show BP 128/82, HR 88, RR 16, temperature 37.2°C, SpO2 98% on room air. Laboratory studies reveal hemoglobin 1…
- USMLE Step 1 · medium45. A 66-year-old man presents with persistent lower back pain and fatigue for three weeks. Vital signs: BP 138/82, HR 92, RR 16, Temp 37.2°C, SpO2 98%. Laboratory studies reveal no…
- USMLE Step 1 · medium46. A 58-year-old man comes to the physician because of fatigue and recurrent infections. Examination shows massive splenomegaly without significant lymphadenopathy. Laboratory stud…
- USMLE Step 1 · medium47. A 71-year-old man presents for evaluation after routine blood work reveals WBC 38,000/mm³. He reports feeling well with no constitutional symptoms. Vital signs are normal: BP 13…
- USMLE Step 1 · medium48. A 6-year-old boy is brought to the physician because of fatigue, fever, and leg pain for 3 weeks. Examination shows pallor, cervical lymphadenopathy, and hepatosplenomegaly. Lab…