Endocrine Pharmacology USMLE Step 1 Practice Questions
100 board-style USMLE Step 1 questions in Pharmacology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · easy73. A 28-year-old woman presents to her gynecologist reporting six months of absent menstrual periods, spontaneous milky nipple discharge from both breasts, and inability to conceiv…
- USMLE Step 1 · hard74. A 51-year-old man with acromegaly underwent transsphenoidal surgery 6 months ago. Despite treatment, he remains symptomatic with coarse facial features and hand enlargement. Cur…
- USMLE Step 1 · medium75. A 43-year-old man presents to his endocrinologist with a 3-year history of progressively enlarging hands and feet, coarsening of facial features, and excessive sweating that soa…
- USMLE Step 1 · hard76. A 39-year-old woman with Cushing disease presents for pituitary ACTH reserve testing. Vital signs show BP 148/92, HR 88, RR 14, Temp 37°C. She has central obesity and proximal m…
- USMLE Step 1 · hard77. A 37-year-old man with small cell lung carcinoma presents with ectopic ACTH production causing severe hypercortisolism. Vital signs show BP 168/98 mmHg, HR 102/min, RR 18/min, t…
- USMLE Step 1 · medium78. A 24-year-old woman with autoimmune primary adrenal insufficiency on hydrocortisone 20 mg daily presents with orthostatic dizziness and intense salt craving for two weeks. Vital…
- USMLE Step 1 · medium79. A 45-year-old woman presents with a 9-month history of progressive hirsutism, proximal muscle weakness, and central obesity with violaceous striae on her abdomen. She reports ea…
- USMLE Step 1 · easy80. A 58-year-old woman with severe rheumatoid arthritis treated with daily oral glucocorticoids for 9 months presents with proximal muscle weakness, thin skin, easy bruising, and h…
- USMLE Step 1 · hard81. A 42-year-old woman with refractory Graves disease presents with tachycardia (HR 118/min), tremor, and heat intolerance. She began propylthiouracil one month ago. Pre-operative…
- USMLE Step 1 · hard82. A 34-year-old woman with a known history of Graves' disease who ran out of her methimazole prescription three weeks ago is brought to the emergency department by her husband, wh…
- USMLE Step 1 · medium83. A 31-year-old woman with Graves disease presents with fever (38.9°C), severe pharyngitis, and malaise 6 weeks after initiating antithyroid therapy. Vital signs show tachycardia…
- USMLE Step 1 · medium84. A 26-year-old woman at 8 weeks' gestation presents with thyroid tenderness, heat intolerance, and palpitations. Vital signs show BP 138/82 mmHg, HR 108/min, RR 18/min, and tempe…
- USMLE Step 1 · medium85. A 35-year-old woman with Hashimoto thyroiditis started levothyroxine replacement 3 months ago. She presents with persistent fatigue, constipation, and weight gain despite medica…
- USMLE Step 1 · hard86. A 29-year-old woman with a 12-year history of type 1 diabetes mellitus presents to her endocrinologist for a follow-up visit regarding persistent postprandial glucose excursions…
- USMLE Step 1 · medium87. A 64-year-old woman with type 2 diabetes mellitus presents with predominantly postprandial hyperglycemia (fasting glucose 118 mg/dL, postprandial glucose 285 mg/dL). She initiat…
- USMLE Step 1 · easy88. A 57-year-old man with type 2 diabetes mellitus started an oral antihyperglycemic agent two months ago. He now presents with polyuria and recurrent candidal balanitis. Vital sig…
- USMLE Step 1 · medium89. A 66-year-old woman with type 2 diabetes mellitus presents with fasting glucose of 156 mg/dL and HbA1c of 8.2%. Vital signs show BP 138/82 mmHg, HR 78/min, RR 16/min, and temper…
- USMLE Step 1 · easy90. A 43-year-old woman with a 6-year history of obesity and type 2 diabetes mellitus presents to her primary care physician for a routine follow-up. Her current medications include…
- USMLE Step 1 · medium91. A 59-year-old woman with type 2 diabetes mellitus and a history of compensated heart failure with reduced ejection fraction (last echocardiogram showing EF of 40%) presents to h…
- USMLE Step 1 · medium92. A 60-year-old man with type 2 diabetes mellitus presents with a fasting glucose of 118 mg/dL but postprandial glucose of 320 mg/dL due to irregular meal timing. Vital signs: BP…
- USMLE Step 1 · hard93. A 67-year-old man with type 2 diabetes mellitus on metformin presents with acute onset facial flushing, nausea, and palpitations 15 minutes after consuming wine at dinner. Vital…
- USMLE Step 1 · easy94. A 55-year-old woman with type 2 diabetes mellitus presents with fatigue and polyuria. Vital signs show BP 138/82 mmHg, HR 88/min, RR 16/min, temperature 37°C, SpO2 98% on room a…
- USMLE Step 1 · medium95. A 62-year-old woman with a 12-year history of type 2 diabetes mellitus comes to the clinic because of progressive fatigue, weakness, and numbness and tingling of her feet over t…
- USMLE Step 1 · easy96. A 49-year-old obese man presents to his primary care physician for a routine follow-up after being diagnosed with type 2 diabetes mellitus three weeks ago during an employee hea…