Endocrine Pharmacology USMLE Step 1 Practice Question
A 51-year-old man with acromegaly underwent transsphenoidal surgery 6 months ago. Despite treatment, he remains symptomatic with coarse facial features and hand enlargement. Current vital signs: BP 145/92 mmHg, HR 88/min. Laboratory studies show elevated IGF-1 (520 ng/mL; normal <300) and growth hormone 8.5 ng/mL. MRI shows no residual pituitary adenoma. He denies headaches or vision changes. His endocrinologist prescribes a drug blocking peripheral growth hormone receptors rather than inhibiting pituitary hormone release. Which agent was most likely prescribed?
Answer choices
- APegvisomantCorrect answer
- BClomiphene
- CCabergoline
- DOctreotide
- ELeuprolide
- FPasireotide
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