Diabetes Mellitus USMLE Step 1 Practice Questions
84 board-style USMLE Step 1 questions in Endocrinology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard1. A 53-year-old man presents with a 6-month history of fatigue, chronic diarrhea, and 8-kg weight loss. He reports a recurrent blistering rash that appears in crops on his lower e…
- USMLE Step 1 · hard2. A 7-year-old girl presents with vaginal bleeding, café au lait macules with irregular borders, and polyostotic fibrous dysplasia on skeletal survey. Vital signs show BP 105/68,…
- USMLE Step 1 · easy3. A 52-year-old man with central obesity, hypertension, and acanthosis nigricans presents with polyuria and polydipsia. Vital signs show BP 148/92 mmHg, HR 88/min, RR 16/min, temp…
- USMLE Step 1 · medium4. A 33-year-old man with poorly controlled type 2 diabetes presents with decreased libido and infertility. He has used metoclopramide chronically for severe gastroparesis. Vital s…
- USMLE Step 1 · medium5. A 31-year-old pregnant woman at 26 weeks gestation presents with fatigue and polyuria. Vital signs: BP 118/76 mmHg, HR 88/min, RR 16/min, temp 37°C. Fasting glucose is 126 mg/dL…
- USMLE Step 1 · hard6. A 9-year-old boy presents with progressive headaches, growth failure, and visual field defects. Vital signs show BP 98/62, HR 88, RR 18, temp 37°C, SpO2 98%. He denies polyuria…
- USMLE Step 1 · hard7. A 30-year-old woman presents 4 months postpartum with amenorrhea, fatigue, and galactorrhea cessation despite attempting breastfeeding. She experienced severe postpartum hemorrh…
- USMLE Step 1 · medium8. A 43-year-old man presents with progressive coarsening of facial features and hand enlargement over 5 years. Vital signs show BP 148/92 mmHg, HR 88/min, RR 16/min, temperature 3…
- USMLE Step 1 · medium9. A 52-year-old woman presents with hot flashes, night sweats, and sleep disturbance. Her menstrual periods have been irregular for 8 months and absent for the past 2 months. Vita…
- USMLE Step 1 · hard10. A 19-year-old man presents with infertility and gynecomastia. Vital signs are normal (BP 118/76, HR 72, RR 16, Temp 37°C). Physical examination reveals tall stature with disprop…
- USMLE Step 1 · easy11. A 15-year-old girl presents with primary amenorrhea and short stature. Vital signs show BP 138/82 mmHg, HR 78/min, RR 16/min, temp 37°C. Physical examination reveals webbed neck…
- USMLE Step 1 · medium12. A 46,XY newborn presents with ambiguous external genitalia and cryptorchidism. At age 13, he develops progressive virilization with increased muscle mass, deepening voice, and f…
- USMLE Step 1 · medium13. A 16-year-old adolescent raised as a girl presents with primary amenorrhea. She is tall (height 5'10"), has normal breast development (Tanner stage V), but scant pubic hair (Tan…
- USMLE Step 1 · medium14. A 17-year-old boy presents with absent pubertal development. Vital signs show BP 110/70 mmHg, HR 82/min, RR 16/min, temperature 37°C. He has sparse facial hair, small testes (8…
- USMLE Step 1 · medium15. A 24-year-old woman with central obesity and acanthosis nigricans presents with irregular menses, infertility, acne, and progressive hirsutism. Vital signs: BP 138/88 mmHg, HR 8…
- USMLE Step 1 · easy16. A 47-year-old woman with type 2 diabetes presents with 4 months of large-volume watery diarrhea persisting during fasting. Vital signs show BP 118/76, HR 102, RR 18, temp 37°C.…
- USMLE Step 1 · medium17. A 59-year-old man presents with chronic steatorrhea, mild diabetes, and recurrent abdominal pain. Vital signs show BP 128/82 mmHg, HR 92/min, RR 16/min, temp 37.2°C, and SpO2 98…
- USMLE Step 1 · medium18. A 55-year-old woman presents with progressive weight loss and a 3-month history of a recurrent erythematous, vesicular rash affecting the groin and perioral regions. Vital signs…
- USMLE Step 1 · medium19. A 43-year-old woman presents with recurrent episodes of confusion, diaphoresis, and tremor that resolve within minutes of eating. During a symptomatic episode, vital signs show…
- USMLE Step 1 · hard20. A 72 year old man with type 2 diabetes is brought for confusion after several days of poor water intake and urinary frequency. Glucose is 920 mg/dL, serum osmolality is markedly…
- USMLE Step 1 · easy21. A 19 year old woman with type 1 diabetes is brought for abdominal pain, vomiting, and rapid deep breathing after missing several insulin doses. Laboratory studies show glucose 5…
- USMLE Step 1 · easy22. A 14-year-old boy presents with polyuria, polydipsia, weight loss, and fatigue for 2 weeks. Vital signs show BP 118/72 mmHg, HR 102 bpm, RR 20/min, temperature 37.2°C, and SpO2…
- USMLE Step 1 · medium23. A 19-year-old man with marfanoid habitus presents with multiple mucosal neuromas on his lips and tongue. Vital signs show BP 156/94 mmHg, HR 108 bpm, RR 16, temp 37°C. He denies…
- USMLE Step 1 · medium24. A 35-year-old woman presents with episodic severe headaches and diaphoresis. Vital signs show BP 168/104 mmHg, HR 102 bpm, RR 16, temperature 37.2°C. Physical examination reveal…