Diabetes Mellitus USMLE Step 1 Practice Question
A 43-year-old man presents with progressive coarsening of facial features and hand enlargement over 5 years. Vital signs show BP 148/92 mmHg, HR 88/min, RR 16/min, temperature 37°C. Random serum growth hormone level is 2.1 ng/mL (often normal). Fasting glucose is elevated at 118 mg/dL. Physical examination reveals no galactorrhea. Which of the following is the best next test to confirm acromegaly?
Answer choices
- A24 hour urinary catecholamines
- BWater deprivation test
- CCosyntropin stimulation test
- DSerum ACTH level
- EMeasure IGF 1 levelCorrect answer
- FSerum IGF-1 measurement as the confirmatory test
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