Chronic Kidney Disease USMLE Step 1 Practice Questions
66 board-style USMLE Step 1 questions in Nephrology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium25. A 17-year-old boy is referred for severe hypertension (BP 168/102 mmHg, HR 88, RR 16, temp 37°C) discovered during a sports physical. Laboratory studies reveal hypokalemia (K+ 2…
- USMLE Step 1 · medium26. A 22-year-old woman presents with progressive fatigue and episodic muscle weakness. Vital signs: BP 118/76 mmHg, HR 92/min, RR 16/min, temp 37°C. Serum potassium 2.8 mEq/L, magn…
- USMLE Step 1 · medium27. A 14-year-old boy presents with progressive muscle cramps and lightheadedness. Vital signs show BP 96/58 mmHg, HR 102/min, RR 18/min. Labs reveal hypokalemic metabolic alkalosis…
- USMLE Step 1 · medium28. A 63-year-old man with long-standing diabetes mellitus presents for routine follow-up. Vital signs: BP 142/88 mmHg, HR 76/min, RR 16/min, temp 37.2°C. He takes lisinopril daily.…
- USMLE Step 1 · hard29. A 6-year-old boy presents with growth failure, polyuria, bone pain, and generalized weakness. Vital signs show BP 118/76 mmHg, HR 92/min, RR 20/min, temperature 37°C, and SpO2 9…
- USMLE Step 1 · medium30. A 34-year-old woman with Sjogren syndrome presents with fatigue and recurrent nephrolithiasis. Vital signs: BP 132/88 mmHg, HR 92 bpm, RR 16/min, Temp 37.2°C, SpO2 98% on room a…
- USMLE Step 1 · easy31. A 54-year-old man receiving induction chemotherapy for acute leukemia presents with sudden left flank pain and gross hematuria. Vital signs: BP 138/82, HR 92, RR 18, Temp 37.2°C…
- USMLE Step 1 · medium32. A 58-year-old man with poorly controlled diabetes mellitus (HbA1c 9.2%) and chronic NSAIDs use presents with gross hematuria and colicky left flank pain. Vital signs: BP 156/92,…
- USMLE Step 1 · medium33. A 47-year-old woman presents with fever (38.8°C), pruritic rash, and left flank pain 10 days after initiating omeprazole for reflux. Vital signs show BP 142/88 mmHg, HR 98/min,…
- USMLE Step 1 · medium34. A 29 year old man is brought to the emergency department after being found confused in a garage. He is tachypneic. Laboratory studies show an elevated anion gap metabolic acidos…
- USMLE Step 1 · medium35. A 72-year-old man with hypertension develops oliguria after prolonged hypotension (BP 78/52 mmHg) during septic shock. Over 48 hours, serum creatinine rises from 1.2 to 4.8 mg/d…
- USMLE Step 1 · hard36. A 61 year old woman with longstanding chronic kidney disease presents with fatigue and recurrent epistaxis. She has no family history of bleeding disorders. Laboratory studies s…
- USMLE Step 1 · medium37. A 64-year-old man with a 10-year history of multiple myeloma presents with progressive lower extremity edema. Vital signs show BP 142/88, HR 88, RR 16, Temp 37.2°C. Urinalysis r…
- USMLE Step 1 · medium38. A 58 year old man with a 15 year history of type 2 diabetes mellitus is found to have persistent albuminuria on repeated testing. He also has diabetic retinopathy. His physician…
- USMLE Step 1 · medium39. A 33 year old man with untreated HIV presents with worsening edema and frothy urine. Laboratory studies show hypoalbuminemia and heavy proteinuria. Kidney biopsy demonstrates sc…
- USMLE Step 1 · medium40. A 5 year old boy is evaluated for generalized edema that began 4 days after a viral upper respiratory infection. Urinalysis shows 4+ protein with no blood. Serum albumin is low…
- USMLE Step 1 · medium41. A 7 year old boy is brought to the clinic because of facial puffiness and dark urine. Three weeks ago he had impetigo that was treated symptomatically at home. He now has blood…
- USMLE Step 1 · easy42. A 19 year old college student develops cola colored urine 1 day after the onset of sore throat and fever. He has had two similar episodes after respiratory infections in the pas…
- USMLE Step 1 · medium43. A 27 year old man comes to the emergency department with hemoptysis, dark urine, and fatigue for 5 days. He has blood pressure of 168/98 mm Hg and mild periorbital edema. Urinal…
- USMLE Step 1 · easy44. A 42 year old man presents with progressive leg swelling and foamy urine for 2 months. He has no hematuria or dysuria. Blood pressure is 146/92 mm Hg. Examination shows periorbi…
- USMLE Step 1 · medium45. A 62-year-old man with stage 4 chronic kidney disease presents with diffuse bone pain and pruritus. Vital signs: BP 152/88, HR 82, RR 16, Temp 37°C, SpO2 98%. Laboratory studies…
- USMLE Step 1 · medium46. A 7-year-old boy presents with growth delay and bone pain. Vital signs show BP 118/76 mmHg, HR 92 bpm, RR 20/min, temp 37°C, SpO2 98%. Labs reveal metabolic acidosis (pH 7.28),…
- USMLE Step 1 · medium47. A 34-year-old woman preparing for a high-altitude trek is started on acetazolamide prophylaxis. She presents with BP 118/76 mmHg, HR 88/min, RR 20/min, and SpO2 98% on room air.…
- USMLE Step 1 · medium48. A 54-year-old woman with recurrent calcium nephrolithiasis and hypertension (BP 158/92 mmHg, HR 78/min) is started on hydrochlorothiazide. Recent labs show serum creatinine 1.2…