Chronic Kidney Disease USMLE Step 1 Practice Question
A 5 year old boy is evaluated for generalized edema that began 4 days after a viral upper respiratory infection. Urinalysis shows 4+ protein with no blood. Serum albumin is low and cholesterol is elevated. Kidney biopsy on light microscopy would most likely appear normal. Which of the following best explains why this child usually responds well to glucocorticoids?
Answer choices
- AThe disease is caused by fibrin thrombi in glomerular capillaries
- BThe disease is caused by immune complex deposition in the subendothelial space
- CThe disease is mediated by T cell cytokine injury to podocytesCorrect answer
- DThe disease is caused by inherited absence of type IV collagen
- EThe disease is caused by anti phospholipase A2 receptor antibodies
- FThe disease is caused by complement-mediated damage to the glomerular basement membrane
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