Chronic Kidney Disease USMLE Step 1 Practice Question
A 42 year old man presents with progressive leg swelling and foamy urine for 2 months. He has no hematuria or dysuria. Blood pressure is 146/92 mm Hg. Examination shows periorbital edema and bilateral pitting edema. Laboratory studies show serum albumin 2.1 g/dL, total cholesterol 320 mg/dL, and urinalysis with 4+ protein but no red blood cell casts. Loss of which of the following proteins most directly explains his increased risk of renal vein thrombosis?
Answer choices
- AHaptoglobin
- BCeruloplasmin
- CAlpha-1 antitrypsin
- DTransferrin
- EAntithrombin IIICorrect answer
- FProtein C
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