Chronic Kidney Disease USMLE Step 1 Practice Question
A 27 year old man comes to the emergency department with hemoptysis, dark urine, and fatigue for 5 days. He has blood pressure of 168/98 mm Hg and mild periorbital edema. Urinalysis shows dysmorphic red blood cells and red blood cell casts. Serum creatinine is markedly elevated. Kidney biopsy is most likely to show which of the following findings?
Answer choices
- ANodular mesangial expansion with arteriolar hyalinosis
- BMesangial IgA deposition following mucosal infection
- CEffacement of podocyte foot processes on electron microscopy
- DLinear IgG and C3 deposition along the glomerular basement membrane with crescentsCorrect answer
- ESubepithelial immune complex deposits with a spike and dome appearance
- FGranular IgG and C3 deposition along the glomerular basement membrane with membranoproliferative pattern
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.