Hepatobiliary Disease USMLE Step 1 Practice Questions
54 board-style USMLE Step 1 questions in Gastroenterology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium25. A 48-year-old woman presents with progressive pruritus and fatigue for 3 months. Vital signs: BP 118/76, HR 88, RR 16, Temp 98.6°F, SpO2 98% on room air. Laboratory studies reve…
- USMLE Step 1 · medium26. A 17-year-old boy presents with tremor, dysarthria, and behavioral changes. Vital signs show BP 118/76 mmHg, HR 88/min, RR 16/min, temperature 37°C, and SpO2 98% on room air. He…
- USMLE Step 1 · medium27. A 52-year-old man presents with progressive fatigue, arthralgias, and skin hyperpigmentation. Vital signs show BP 128/82, HR 88, RR 16, temperature 37°C, SpO2 98%. Laboratory st…
- USMLE Step 1 · hard28. A 3-day-old male newborn presents with severe jaundice and lethargy. Vital signs show HR 145/min, RR 48/min, temperature 37.2°C. Laboratory studies reveal unconjugated hyperbili…
- USMLE Step 1 · easy29. A 20-year-old man presents with intermittent jaundice occurring during exam periods and after fasting for 12+ hours. Vital signs are normal (BP 118/76, HR 72, RR 16, Temp 98.6°F…
- USMLE Step 1 · hard30. A 51-year-old woman presents with profuse watery diarrhea persisting during fasting. Vitals show BP 98/62, HR 112, RR 18, temp 37.2°C. She reports weakness and lightheadedness.…
- USMLE Step 1 · medium31. A 36-year-old woman presents with recurrent episodes of diaphoresis, tremor, and confusion that resolve within 15 minutes of consuming juice. During symptomatic episodes, vital…
- USMLE Step 1 · easy32. A 67-year-old man with a 40 pack-year smoking history presents with progressive weight loss, painless jaundice, and dark urine over 3 weeks. Vital signs: BP 138/82, HR 88, RR 16…
- USMLE Step 1 · medium33. A 43-year-old woman with a history of gallstones presents with severe epigastric pain radiating to the back, nausea, and vomiting for 6 hours. Vital signs show BP 128/82 mmHg, H…
- USMLE Step 1 · medium34. A 49-year-old man with a 20-year history of alcohol use presents with bulky, foul-smelling stools, progressive weight loss, and easy bruising. Vital signs show BP 128/76, HR 88,…
- USMLE Step 1 · hard35. A term newborn presents with bilious vomiting 6 hours after birth. Vital signs show HR 145/min, RR 48/min, and mild dehydration. Abdominal examination reveals distension without…
- USMLE Step 1 · easy36. A 2-day-old male presents with a midline abdominal wall defect at the umbilicus containing herniated bowel and liver covered by a translucent membranous sac. Vital signs show HR…
- USMLE Step 1 · easy37. A full-term newborn presents with visible loops of small bowel protruding through a defect in the anterior abdominal wall just lateral to the umbilicus without membranous covera…
- USMLE Step 1 · medium38. A 2-day-old boy presents with bilious vomiting shortly after feeding attempts. Vital signs show HR 145 bpm, RR 32, temperature 37.2°C, BP 65/40. Prenatal ultrasound demonstrated…
- USMLE Step 1 · medium39. A 67-year-old man with a 40 pack-year smoking history presents with progressive painless jaundice, weight loss, and epigastric discomfort over 8 weeks. Vital signs: BP 138/82, H…
- USMLE Step 1 · medium40. A 51-year-old man with 30-year history of heavy alcohol use presents with recurrent epigastric pain, chronic diarrhea, and 10-kg weight loss over 6 months. Vital signs: BP 128/8…
- USMLE Step 1 · easy41. A 43-year-old woman with a history of gallstones presents with severe epigastric pain radiating to the back and repeated vomiting for 6 hours. Vital signs show BP 128/82 mmHg, H…
- USMLE Step 1 · hard42. An 81-year-old woman presents with progressive abdominal distension, bilious vomiting, and obstipation for 3 days. Vital signs show BP 138/82, HR 98, RR 20, temperature 37.2°C,…
- USMLE Step 1 · medium43. A 57-year-old woman with Hashimoto thyroiditis presents with progressive fatigue and intense generalized pruritus for 3 months. Vital signs: BP 128/82 mmHg, HR 76/min, RR 14/min…
- USMLE Step 1 · medium44. A 63-year-old woman with known cholelithiasis presents with fever, jaundice, and right upper quadrant pain. Vital signs show BP 88/54, HR 118, RR 22, temperature 39.2°C, and SpO…
- USMLE Step 1 · hard45. A 27-year-old woman presents with chronic mild jaundice noted on routine examination. Vital signs are stable: BP 118/76 mmHg, HR 82 bpm, RR 16/min, temp 37°C, SpO2 98%. Laborato…
- USMLE Step 1 · medium46. A 21-year-old man presents with intermittent scleral icterus exacerbated by fasting and stress. Vital signs: BP 118/76, HR 82, RR 16, Temp 37°C, SpO2 98%. He denies abdominal pa…
- USMLE Step 1 · hard47. A 35-year-old woman with polycythemia vera presents with acute onset right upper quadrant pain and abdominal distension. Vital signs show BP 128/82 mmHg, HR 98/min, RR 16/min, t…
- USMLE Step 1 · medium48. A 52-year-old man with recently diagnosed diabetes mellitus presents with progressive fatigue, arthralgias, and decreased libido. Vital signs: BP 128/82 mmHg, HR 88/min, RR 16/m…