Hepatobiliary Disease USMLE Step 1 Practice Question
A 36-year-old woman presents with recurrent episodes of diaphoresis, tremor, and confusion that resolve within 15 minutes of consuming juice. During symptomatic episodes, vital signs show HR 102/min, BP 138/88 mmHg, and fingerstick glucose of 42 mg/dL. Laboratory studies reveal elevated insulin (18 mIU/mL) and C-peptide (4.5 ng/mL) concurrent with hypoglycemia. MRI abdomen demonstrates a 1.5-cm pancreatic islet cell tumor. TSH and prolactin levels are normal. Which genetic syndrome is most strongly associated with this neoplasm?
Answer choices
- AVon Hippel-Lindau syndrome
- BLynch syndrome
- CMEN 1Correct answer
- DFamilial adenomatous polyposis
- EMEN 2A
- FNeurofibromatosis type 1
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