Histology USMLE Step 1 Practice Questions
54 board-style USMLE Step 1 questions in Anatomy. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard25. A 3-year-old boy presents to the emergency department with epistaxis and petechiae after a minor fall. His mother reports he bruises easily and had prolonged bleeding after circ…
- USMLE Step 1 · hard26. A 28-year-old man with recurrent urinary tract infections and hematuria presents with BP 128/82 mmHg, HR 92/min, and serum creatinine 1.4 mg/dL. Renal biopsy histology reveals a…
- USMLE Step 1 · medium27. A 42-year-old woman with no significant past medical history presents with progressive dyspnea and a dry cough for 4 months. She denies fever, weight loss, or occupational expos…
- USMLE Step 1 · medium28. A 60-year-old man presents with a 2-year history of progressive dyspnea and chronic nonproductive cough. He denies occupational exposures, smoking history, and medications. Vita…
- USMLE Step 1 · easy29. A 51-year-old woman with a three-year history of progressive dysphagia and chronic GERD presents with dysphagia to solids. Vital signs: BP 128/82, HR 88, RR 16, Temp 37.2°C, SpO…
- USMLE Step 1 · hard30. A 38-year-old man presents with progressive testicular enlargement over 3 months. He reports a painless, firm mass on self-examination. Vital signs are stable. Physical examinat…
- USMLE Step 1 · medium31. A 42-year-old woman with a 5-year history of rheumatoid arthritis presents to clinic with complaints of bilateral knee pain, swelling, and morning stiffness lasting 2 hours. Vit…
- USMLE Step 1 · medium32. A 28-year-old woman presents with amenorrhea for 8 months and galactorrhea. Vital signs show BP 118/76, HR 82, RR 16, Temp 37°C. Laboratory studies reveal prolactin 285 ng/mL (n…
- USMLE Step 1 · medium33. A 32-year-old man with a 6-year history of ulcerative colitis presents with bloody diarrhea, tenesmus, and left lower quadrant abdominal pain. Vital signs: HR 94/min, BP 119/75…
- USMLE Step 1 · hard34. A 31-year-old woman in labor undergoes cesarean delivery for arrest of descent. A biopsy specimen from the uterine wall is examined for teaching purposes. The predominant contra…
- USMLE Step 1 · medium35. A 68-year-old man with hypertension (BP 165/95 mmHg, HR 108/min, RR 20/min) dies from acute myocardial infarction complications. Autopsy reveals elevated cardiac troponin I (8.2…
- USMLE Step 1 · medium36. A 72-year-old woman with osteoporosis (bone mineral density T-score −2.8) falls and sustains a femoral neck fracture. Intraoperatively, vital signs are stable (BP 138/82, HR 88,…
- USMLE Step 1 · medium37. A 19-year-old male athlete presents with acute left knee pain following a twisting injury during soccer. Vital signs: BP 118/76, HR 92, RR 16, Temp 37°C, SpO2 98%. MRI reveals a…
- USMLE Step 1 · easy38. A 23-year-old man sustains a deep laceration across the palm while cooking. Vital signs are stable: BP 118/76 mmHg, HR 88/min, RR 16/min. During surgical repair, the surgeon obs…
- USMLE Step 1 · medium39. A 63-year-old woman presents with recurrent nephrolithiasis and fatigue. Vital signs: BP 138/88 mmHg, HR 92/min, RR 14/min, temperature 37.2°C. Serum calcium is 11.2 mg/dL (norm…
- USMLE Step 1 · medium40. A 36-year-old woman presents with a palpable thyroid nodule discovered on routine examination. Vital signs are normal (BP 118/76 mmHg, HR 72 bpm, RR 16, Temp 37°C). TSH is norma…
- USMLE Step 1 · hard41. A 55-year-old man with cirrhosis presents with jaundice, ascites, and hepatic encephalopathy. Vital signs show BP 110/70, HR 92, RR 18, temp 37°C, SpO2 98%. Laboratory studies r…
- USMLE Step 1 · hard42. A 46-year-old man with a 15-year history of heavy alcohol use presents with acute pancreatitis (BP 128/82, HR 102, RR 20, Temp 38.2°C). Serum lipase is elevated at 850 U/L; abdo…
- USMLE Step 1 · medium43. A 58-year-old woman with a 2-year history of autoimmune gastritis presents with macrocytic anemia and paresthesias. Vital signs are stable (BP 128/82, HR 78, RR 16, Temp 37°C).…
- USMLE Step 1 · medium44. A 61-year-old woman with a positive fecal occult blood test undergoes colonoscopy. Vital signs are BP 128/82 mmHg, HR 76/min, RR 14/min, and temperature 37°C. Hemoglobin is 10.2…
- USMLE Step 1 · medium45. A 17-year-old boy presents with a 3-month history of chronic diarrhea and 8-kg weight loss. Vital signs show HR 92/min, BP 110/68 mmHg, temperature 37.2°C. Colonoscopy appears n…
- USMLE Step 1 · medium46. A 48-year-old man with chronic epigastric pain (BP 128/82, HR 88, RR 16, Temp 37.2°C) undergoes upper endoscopy. Duodenal biopsy reveals normal villous architecture with intact…
- USMLE Step 1 · medium47. A 26-year-old woman presents for routine cervical cancer screening with vital signs BP 118/76, HR 82, RR 16, Temp 98.6°F, SpO2 98%. Pap smear reveals atypical squamous cells. Th…
- USMLE Step 1 · medium48. A 38-year-old man undergoing vasectomy for permanent contraception has a resected specimen showing a thick-walled tube with a small stellate lumen. Vital signs are stable (BP 11…