Histology USMLE Step 1 Practice Question
A 26-year-old woman presents for routine cervical cancer screening with vital signs BP 118/76, HR 82, RR 16, Temp 98.6°F, SpO2 98%. Pap smear reveals atypical squamous cells. The clinician intentionally samples the transformation zone, where dysplastic lesions commonly arise, because this region represents a specific histologic junction. CT imaging shows no cervical lymphadenopathy. The patient denies abnormal vaginal bleeding. Which epithelial combination characteristically meets at this transformation zone?
Answer choices
- ASimple cuboidal and simple squamous
- BTransitional and simple columnar
- CKeratinized stratified squamous and simple cuboidal
- DSimple columnar and pseudostratified ciliated columnar
- ESimple columnar and nonkeratinized stratified squamousCorrect answer
- FKeratinized stratified squamous and pseudostratified ciliated columnar
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