Histology USMLE Step 1 Practice Question
A 55-year-old man with cirrhosis presents with jaundice, ascites, and hepatic encephalopathy. Vital signs show BP 110/70, HR 92, RR 18, temp 37°C, SpO2 98%. Laboratory studies reveal elevated transaminases and INR 2.1. Ultrasound confirms cirrhosis with portal hypertension. Liver biopsy shows fibrotic regions with bridging fibrosis. In normal hepatic architecture adjacent to fibrotic areas, the pathologist identifies specialized macrophages within sinusoidal spaces. No malignancy is noted. These cells are most likely which of the following?
Answer choices
- AChief cells
- BKupffer cellsCorrect answer
- CIto cells
- DCentroacinar cells
- EM cells
- FHepatic stellate cells
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