Histology USMLE Step 1 Practice Question
A 63-year-old woman presents with recurrent nephrolithiasis and fatigue. Vital signs: BP 138/88 mmHg, HR 92/min, RR 14/min, temperature 37.2°C. Serum calcium is 11.2 mg/dL (normal 8.5-10.2), with PTH elevated at 145 pg/mL. Urinalysis shows no hematuria. CT imaging reveals a 1.2-cm left parathyroid adenoma. Parathyroid exploration is performed. The normal parathyroid tissue not involved by the adenoma would most likely demonstrate which of the following histologic features?
Answer choices
- AIslets surrounded by pancreatic acini
- BChromaffin cells derived from neural crest
- CColloid-filled follicles lined by cuboidal epithelium
- DCords of chief cells with scattered oxyphil cellsCorrect answer
- EZona fasciculata with lipid-rich cells
- FWater-clear cells arranged in sheets
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