Neoplasia USMLE Step 1 Practice Questions
56 board-style USMLE Step 1 questions in Pathology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 Ā· medium25. A 65-year-old man with a 40-pack-year smoking history presents to the emergency department with hemoptysis and a 3-week productive cough. He reports constitutional symptoms areā¦
- USMLE Step 1 Ā· easy26. A 44-year-old woman presents to the emergency department with vaginal bleeding and pelvic pressure for 3 months. She denies fever, chills, or vaginal discharge. Past medical hisā¦
- USMLE Step 1 Ā· hard27. A 67-year-old man with a 10-year history of Barrett esophagus presents to the gastroenterology clinic with progressive dysphagia to solids and unintentional weight loss of 8 kgā¦
- USMLE Step 1 Ā· medium28. A 28-year-old man with neurofibromatosis type 1 presents with progressive back pain and dyspnea. Vital signs show BP 128/82, HR 92, RR 20, SpO2 94% on room air. MRI reveals a laā¦
- USMLE Step 1 Ā· medium29. A 63-year-old woman with a 15-year history of Paget disease presents with acute left leg pain, swelling, and immobility. Vital signs: BP 128/82, HR 92, RR 16, Temp 37.2Ā°C, SpO2ā¦
- USMLE Step 1 Ā· easy30. A 56-year-old woman presents with progressive vision loss and floaters over 2 months. She reports no eye pain or photopsia. Vital signs are stable. Ophthalmologic examination reā¦
- USMLE Step 1 Ā· medium31. A 72-year-old man with a 15-year history of hepatitis C cirrhosis presents to clinic with right upper quadrant pain for 2 weeks. He denies fever, jaundice, or weight loss. Vitalā¦
- USMLE Step 1 Ā· medium32. A 34-year-old man presents to urology clinic with a 3-week history of painless left testicular enlargement. He denies constitutional symptoms. Vital signs are stable. Physical eā¦
- USMLE Step 1 Ā· medium33. A 52-year-old woman presents with a palpable left breast mass discovered on self-examination. Vital signs: BP 128/82, HR 92, RR 16, Temp 37Ā°C, SpO2 98% on room air. Mammographyā¦
- USMLE Step 1 Ā· easy34. A 67-year-old man with a 40 pack-year smoking history presents with progressive weight loss, painless jaundice, and dark urine for 3 weeks. Vital signs show BP 138/82, HR 92, RRā¦
- USMLE Step 1 Ā· hard35. A 38-year-old woman with family history of multiple endocrine neoplasia type 2A presents with a palpable thyroid nodule. Vital signs: BP 128/82 mmHg, HR 88/min, RR 16/min, Tempā¦
- USMLE Step 1 Ā· hard36. A 67-year-old man with a 3-month history of progressive weight loss and epigastric pain radiating to the back presents with painless jaundice. Vital signs: BP 128/82, HR 94, RRā¦
- USMLE Step 1 Ā· hard37. A 2-year-old boy presents with a painless left testicular mass and scrotal swelling. Vital signs show BP 95/60, HR 110, RR 22, temp 37.2Ā°C, SpO2 98%. Serum Ī±-fetoprotein (AFP) iā¦
- USMLE Step 1 Ā· hard38. A 3-year-old boy presents with an abdominal mass discovered by his parents. Vital signs are stable (BP 95/60, HR 110, RR 24, Temp 37Ā°C, SpO2 98%). Abdominal ultrasound reveals aā¦
- USMLE Step 1 Ā· hard39. A 51-year-old woman presents with vaginal bleeding and pelvic pain. Vital signs show BP 128/82 mmHg, HR 92/min, RR 16/min, temp 37.2Ā°C. Pelvic ultrasound reveals a large heterogā¦
- USMLE Step 1 Ā· hard40. A 47-year-old man presents with a rapidly enlarging, painless deep thigh mass. Vital signs include BP 128/82 mmHg, HR 92/min, RR 16/min, temperature 37.2Ā°C, and SpO2 98% on roomā¦
- USMLE Step 1 Ā· hard41. A 59-year-old woman presents with right upper quadrant pain, weight loss, and jaundice. Vital signs show BP 128/82, HR 92, RR 16, Temp 37.2Ā°C, SpO2 98%. CT abdomen reveals a 4-cā¦
- USMLE Step 1 Ā· hard42. A 66-year-old man with metastatic non-small cell lung carcinoma (PD-L1 expression >50% on immunohistochemistry) presents with cough and dyspnea. Vital signs: BP 138/82, HR 92, Rā¦
- USMLE Step 1 Ā· hard43. A 60-year-old man presents with recurrent upper gastrointestinal bleeding. Vital signs show BP 128/82 mmHg, HR 92/min, RR 16/min, temp 37.2Ā°C. Hemoglobin is 9.8 g/dL. Upper endoā¦
- USMLE Step 1 Ā· hard44. A 31 year old woman has an abnormal Pap smear showing high grade squamous intraepithelial lesion. Cervical biopsy demonstrates dysplastic squamous epithelium caused by persistenā¦
- USMLE Step 1 Ā· hard45. A 68-year-old man presents with a 3-month history of bloody diarrhea and weight loss. Colonoscopy reveals a 4-cm mass in the sigmoid colon; biopsy confirms adenocarcinoma. A tumā¦
- USMLE Step 1 Ā· hard46. A 43-year-old woman presents with progressive early satiety and 8-kg weight loss over three months. Vital signs show BP 118/76, HR 92, RR 16, temp 37.2Ā°C, SpO2 98%. Upper endoscā¦
- USMLE Step 1 Ā· medium47. A 63-year-old man presents with progressive fatigue, nephrotic-range proteinuria (8.5 g/day), and bilateral foot numbness. Vital signs show BP 138/82, HR 88, RR 16, Temp 37.2Ā°C,ā¦
- USMLE Step 1 Ā· easy48. A 58 year old woman is evaluated for fatigue, constipation, and recurrent kidney stones. She has bone pain and a serum calcium of 12.8 mg/dL with elevated parathyroid hormone. Cā¦