Neoplasia USMLE Step 1 Practice Question
A 65-year-old man with a 40-pack-year smoking history presents to the emergency department with hemoptysis and a 3-week productive cough. He reports constitutional symptoms are absent. Vital signs: BP 138/82, HR 92, RR 18, temperature 37.2°C, SpO2 94% on room air. Chest X-ray shows a 3 cm cavitary lesion in the right upper lobe with irregular borders. Bronchoscopy with bronchoalveolar lavage reveals atypical cells with abundant keratin material and intercellular bridging on histology. Fungal and mycobacterial cultures are negative. Which of the following is the most likely diagnosis?
Answer choices
- ASmall cell lung carcinoma
- BSquamous cell carcinoma of the lungCorrect answer
- CAdenocarcinoma of the lung
- DLarge cell carcinoma of the lung
- EPulmonary carcinoid tumor
- FMucoepidermoid carcinoma of the lung
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