Neoplasia USMLE Step 1 Practice Question
A 2-year-old boy presents with a painless left testicular mass and scrotal swelling. Vital signs show BP 95/60, HR 110, RR 22, temp 37.2°C, SpO2 98%. Serum α-fetoprotein (AFP) is markedly elevated at 8,500 ng/mL; β-hCG is normal. Abdominal ultrasound reveals no metastases. Pathology confirms yolk sac tumor. Which tumor marker correlates most closely with disease burden and prognosis?
Answer choices
- ACalcitonin
- BCarcinoembryonic antigen
- CAlpha fetoproteinCorrect answer
- DProstate specific antigen
- ECancer antigen 125
- FHuman chorionic gonadotropin
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