Neoplasia USMLE Step 1 Practice Question
A 51-year-old woman presents with vaginal bleeding and pelvic pain. Vital signs show BP 128/82 mmHg, HR 92/min, RR 16/min, temp 37.2°C. Pelvic ultrasound reveals a large heterogeneous uterine mass measuring 12 cm. Pathology demonstrates atypical spindle cells with 25 mitoses per 10 high-power fields. Immunohistochemistry shows negative CD117 and DOG1 stains. The pathologist suspects leiomyosarcoma. Which marker would most likely stain positive in these tumor cells?
Answer choices
- ACD20
- BGFAP
- CTTF 1
- DSynaptophysin
- EDesminCorrect answer
- FHMB-45
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