Diabetes Mellitus USMLE Step 1 Practice Questions
84 board-style USMLE Step 1 questions in Endocrinology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard49. A 6-year-old girl presents with early pubic hair development and accelerated linear growth. Vital signs reveal BP 145/92 mmHg, HR 88 bpm, RR 18, temp 37°C, SpO2 98%. Laboratory…
- USMLE Step 1 · medium50. A newborn girl with ambiguous genitalia presents on day 8 of life with vomiting and dehydration. Vital signs show BP 55/32 mmHg, HR 158/min, RR 32/min, temperature 36.8°C. Labor…
- USMLE Step 1 · hard51. A 63-year-old woman with type 2 diabetes is started on a drug that binds the nuclear receptor PPAR gamma to improve insulin sensitivity. Three months later she reports lower ext…
- USMLE Step 1 · medium52. A 48-year-old obese woman with type 2 diabetes presents with a 3-month history of improved glycemic control and 8-pound weight loss after initiating a new antidiabetic agent. Vi…
- USMLE Step 1 · medium53. A 60-year-old man with type 2 diabetes mellitus and heart failure presents with fatigue. Vitals: BP 128/76 mmHg, HR 92/min, RR 16/min, Temp 37°C, SpO2 98% on room air. Recent fa…
- USMLE Step 1 · medium54. A 68-year-old man with type 2 diabetes and stage 3 chronic kidney disease on metformin presents with malaise, abdominal discomfort, and tachypnea 6 hours after receiving intrave…
- USMLE Step 1 · medium55. A 63-year-old man with type 2 diabetes presents with fatigue and polyuria. Vital signs show BP 142/88 mmHg, HR 88/min, RR 16/min, temperature 37.2°C, and SpO2 98% on room air. H…
- USMLE Step 1 · medium56. A 22-year-old woman with type 1 diabetes presents with a fasting glucose of 156 mg/dL and HbA1c of 8.2%. She is currently taking only basal insulin glargine and reports inconsis…
- USMLE Step 1 · hard57. A 17-year-old boy with type 1 diabetes mellitus on insulin therapy presents with fasting morning glucose levels of 280 mg/dL. His endocrinologist requests 3 AM glucose checks, w…
- USMLE Step 1 · medium58. A 72-year-old man with type 2 diabetes mellitus is brought to the emergency department with lethargy and severe dehydration after several days of pneumonia. Laboratory studies s…
- USMLE Step 1 · medium59. A 17-year-old girl with type 1 diabetes mellitus presents with abdominal pain, vomiting, and confusion after missing several insulin doses. She is tachypneic and dehydrated. Lab…
- USMLE Step 1 · easy60. A 54-year-old obese man with hypertension and dyslipidemia presents with fatigue. Vital signs show BP 148/92 mmHg, HR 88/min, RR 16/min, temperature 37°C, and SpO2 98% on room a…
- USMLE Step 1 · easy61. A 13-year-old boy presents with polyuria, polydipsia, and nocturia over 2 months with 4-kg weight loss. Vital signs show BP 118/76 mmHg, HR 92 bpm, RR 18/min, temperature 37.2°C…
- USMLE Step 1 · medium62. A 70-year-old woman with limited sun exposure and poor nutritional intake presents with diffuse bone pain and proximal leg weakness. Vital signs: BP 138/82, HR 88, RR 16, Temp 3…
- USMLE Step 1 · medium63. A 58-year-old woman with metastatic lung cancer presents with confusion and nausea. Vital signs show BP 128/76 mmHg, HR 88/min, RR 14/min, temperature 37°C. Serum sodium is 118…
- USMLE Step 1 · easy64. A 66-year-old man with newly diagnosed small cell lung carcinoma presents with confusion and nausea. Vital signs show BP 128/76 mmHg, HR 88/min, RR 16/min, temperature 37.2°C, a…
- USMLE Step 1 · medium65. A 42-year-old man with bipolar disorder presents with persistent polyuria and polydipsia. Vital signs show BP 128/82 mmHg, HR 88 bpm, RR 16/min, temp 37°C. Labs reveal serum sod…
- USMLE Step 1 · medium66. A 27-year-old man develops intense thirst and polyuria 1 week after a traumatic brain injury. Serum sodium is 151 mEq/L, serum osmolality is elevated, and urine osmolality is lo…
- USMLE Step 1 · medium67. A 30-year-old woman presents 2 months after a complicated delivery with massive postpartum hemorrhage requiring transfusion. She reports inability to lactate, fatigue, cold into…
- USMLE Step 1 · medium68. A 46-year-old man with poorly controlled hypertension (BP 168/102 mmHg) reports progressive enlargement of his hands and feet requiring larger shoe sizes over 3 years, along wit…
- USMLE Step 1 · medium69. A 31-year-old woman with schizophrenia started olanzapine 3 months ago and now presents with galactorrhea, amenorrhea, and weight gain. Vital signs: BP 118/76, HR 82, RR 16, Tem…
- USMLE Step 1 · easy70. A 29-year-old woman presents with 6 months of amenorrhea and bilateral galactorrhea. Pregnancy test is negative. She reports decreased libido and mild headaches. Vital signs sho…
- USMLE Step 1 · medium71. A 19-year-old man with a marfanoid body habitus presents with a thyroid nodule. Physical examination reveals mucosal neuromas on the lips and tongue. Vital signs: BP 128/82, HR…
- USMLE Step 1 · medium72. A 35-year-old woman presents with medullary thyroid carcinoma discovered on biopsy. Her brother underwent adrenalectomy for pheochromocytoma (plasma metanephrines elevated at 45…