Diabetes Mellitus USMLE Step 1 Practice Question
A 63-year-old man with type 2 diabetes presents with fatigue and polyuria. Vital signs show BP 142/88 mmHg, HR 88/min, RR 16/min, temperature 37.2°C, and SpO2 98% on room air. His fasting glucose is 185 mg/dL with HbA1c of 8.2%. He denies recent weight loss or infections. His physician initiates therapy with a medication that increases insulin secretion by closing ATP-sensitive potassium channels in pancreatic beta cells. Which drug most likely has this mechanism of action?
Answer choices
- AMetformin
- BGlipizideCorrect answer
- CAcarbose
- DEmpagliflozin
- EPioglitazone
- FSitagliptin
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.