Diabetes Mellitus USMLE Step 1 Practice Question
A 6-year-old girl presents with early pubic hair development and accelerated linear growth. Vital signs reveal BP 145/92 mmHg, HR 88 bpm, RR 18, temp 37°C, SpO2 98%. Laboratory studies show serum cortisol 3 µg/dL (low), plasma renin activity <0.3 ng/mL/hr (low), serum potassium 2.8 mEq/L, and elevated 17-hydroxyprogesterone. No hirsutism is noted. Which of the following is the most likely diagnosis?
Answer choices
- APheochromocytoma
- B11-beta hydroxylase deficiencyCorrect answer
- C21-hydroxylase deficiency
- D17-alpha hydroxylase deficiency
- EPrimary hyperaldosteronism
- F3-beta hydroxysteroid dehydrogenase deficiency
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations ā plus adaptive practice that targets your weak areas ā with a free MedBoardPRO account.