Toxicology USMLE Step 1 Practice Questions
58 board-style USMLE Step 1 questions in Pharmacology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard25. A 76-year-old woman with heart failure and atrial fibrillation taking digoxin presents with nausea, vomiting, and yellow-green halos around lights. Vitals: BP 128/76, HR 102 wit…
- USMLE Step 1 · medium26. A 17-year-old boy develops rapidly increasing core temperature (40.2°C), generalized muscle rigidity, and tachycardia (HR 142/min) shortly after induction of general anesthesia…
- USMLE Step 1 · medium27. A 38-year-old man with schizophrenia presents with fever, confusion, and altered mental status 3 days after initiating high-dose haloperidol. Vital signs show temperature 39.2°C…
- USMLE Step 1 · medium28. A 25-year-old woman taking sertraline 100 mg daily develops agitation, diaphoresis, and diarrhea shortly after starting linezolid for pneumonia. Vital signs show BP 148/92, HR 1…
- USMLE Step 1 · hard29. A 27-year-old woman is brought to the emergency department after ingesting an unknown amount of amitriptyline 2 hours ago. She is confused and disoriented. Vital signs show BP 8…
- USMLE Step 1 · medium30. A 71-year-old woman with atrial fibrillation on warfarin presents with melena and dizziness. Vital signs show BP 92/58, HR 108, RR 20, temp 36.8°C, SpO2 98% on room air. Laborat…
- USMLE Step 1 · medium31. A 6-year-old boy presents with lead poisoning from peeling paint exposure. Vital signs: BP 105/68 mmHg, HR 88/min, RR 20/min, temp 37°C, SpO2 98% on room air. Blood lead level i…
- USMLE Step 1 · medium32. A 43-year-old woman working in artisanal gold extraction presents with tremor, gingival inflammation, and mood changes. Vital signs show BP 128/82 mmHg, HR 92/min, RR 16/min, te…
- USMLE Step 1 · easy33. A 5-year-old boy from an older home with peeling paint presents with developmental delay, abdominal pain, and constipation. Vital signs: BP 102/68 mmHg, HR 98/min, RR 20/min, te…
- USMLE Step 1 · medium34. A 2-year-old boy presents to the emergency department after ingesting his mother's prenatal vitamins. Vital signs show HR 128/min, BP 92/58 mmHg, RR 22/min, and temperature 37.2…
- USMLE Step 1 · medium35. A 3-month-old infant presents to the emergency department with cyanosis following infiltration of lidocaine during a minor surgical procedure. Vital signs show HR 155 bpm, RR 38…
- USMLE Step 1 · medium36. A 28-year-old man is rescued from a burning residential house after being trapped for approximately 20 minutes in an enclosed room. On arrival to the emergency department, he is…
- USMLE Step 1 · easy37. A 35-year-old woman and her two children develop headache, dizziness, and nausea while sleeping in a house with a faulty furnace during winter. The mother presents with BP 128/8…
- USMLE Step 1 · medium38. A 52-year-old man is found confused in his garage beside an open antifreeze container. He presents with flank pain, oliguria, and altered mental status. Vital signs show BP 128/…
- USMLE Step 1 · medium39. A 46-year-old man presents to the emergency department 2 hours after ingesting windshield washer fluid. He is confused and reports blurred vision. Vital signs: BP 118/76 mmHg, H…
- USMLE Step 1 · easy40. A 29-year-old man with a history of intravenous drug use is found unresponsive in a public restroom. Vital signs show BP 88/56, HR 52, RR 5, temperature 36.2°C, and SpO2 78% on…
- USMLE Step 1 · medium41. A 7-year-old boy is brought to the emergency department after ingesting unknown berries from a garden 2 hours ago. He is agitated and hallucinating, with flushed skin, temperatu…
- USMLE Step 1 · easy42. A 41-year-old farm worker is brought to the emergency department after collapsing in a field following acute organophosphate pesticide exposure. He presents with diaphoresis, wh…
- USMLE Step 1 · medium43. A 19-year-old college student is brought to the emergency department after intentionally ingesting a bottle of aspirin tablets. He presents with tinnitus, nausea, and tachypnea…
- USMLE Step 1 · easy44. A 23-year-old woman is brought to the emergency department 8 hours after ingesting approximately 30 tablets of acetaminophen 500 mg during an argument with her partner. She repo…
- USMLE Step 1 · medium45. A 34-year-old woman arrives at the emergency department with somnolence after ingesting excessive diazepam. Vital signs show BP 118/76, HR 88, RR 10, temperature 37°C, and SpO2…
- USMLE Step 1 · easy46. A 25-year-old man with a history of intravenous drug use is found unresponsive with shallow breathing (RR 8/min), bradycardia (HR 52/min), and pinpoint pupils. Vital signs show…
- USMLE Step 1 · medium47. A 29-year-old man is brought to the emergency department after being found in a running car in a closed garage. He presents with severe headache, confusion, and characteristic c…
- USMLE Step 1 · medium48. A 38-year-old industrial worker presents with severe cramping abdominal pain, persistent vomiting, and hypotension (BP 85/52 mmHg, HR 110/min). He reports garlic odor on his bre…