Toxicology USMLE Step 1 Practice Question
A 27-year-old woman is brought to the emergency department after ingesting an unknown amount of amitriptyline 2 hours ago. She is confused and disoriented. Vital signs show BP 85/52 mmHg, HR 118/min, RR 22/min, temperature 37.8°C, and SpO2 98% on room air. ECG demonstrates a QRS duration of 160 ms. Serum bicarbonate is 22 mEq/L. She denies acetaminophen ingestion. Which of the following is the most appropriate treatment?
Answer choices
- AN-acetylcysteine
- BPhysostigmine
- CHaloperidol
- DSodium bicarbonateCorrect answer
- EFlumazenil
- FActivated charcoal followed by hemodialysis
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