Toxicology USMLE Step 1 Practice Question
A 41-year-old farm worker is brought to the emergency department after collapsing in a field following acute organophosphate pesticide exposure. He presents with diaphoresis, wheezing, miosis, muscle fasciculations, and diarrhea. Vital signs show BP 98/62, HR 48, RR 28, SpO2 88% on room air. Serum cholinesterase is markedly decreased at 15% of normal. He denies chest pain. Which of the following is the most appropriate initial pharmacologic treatment?
Answer choices
- ANaloxone plus atropine
- BPhysostigmine only
- CAtropine plus pralidoximeCorrect answer
- DFlumazenil plus pralidoxime
- EMethylene blue
- FPhysostigmine plus atropine
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