Toxicology USMLE Step 1 Practice Question
A 71-year-old woman with atrial fibrillation on warfarin presents with melena and dizziness. Vital signs show BP 92/58, HR 108, RR 20, temp 36.8°C, SpO2 98% on room air. Laboratory studies reveal INR 7.8, hemoglobin 7.2 g/dL (previously 12.1), and normal platelet count. She denies recent trauma or falls. She is actively bleeding from the gastrointestinal tract. Which of the following is the most appropriate immediate management?
Answer choices
- AHold warfarin and repeat INR tomorrow
- BAdminister vitamin K alone
- CAdminister idarucizumab
- DAdminister 4-factor prothrombin complex concentrate plus vitamin KCorrect answer
- EAdminister protamine sulfate
- FFresh frozen plasma
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