Pituitary Disorders USMLE Step 1 Practice Questions
57 board-style USMLE Step 1 questions in Endocrinology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · easy25. A 45-year-old man presents with progressive frontal headaches, bitemporal hemianopsia, and erectile dysfunction for 3 months. Vital signs: BP 138/88 mmHg, HR 76/min, RR 14/min,…
- USMLE Step 1 · easy26. A 48-year-old woman with a history of prolactinoma managed with cabergoline presents with acute severe headache, bitemporal hemianopsia, and confusion. Vital signs show BP 148/9…
- USMLE Step 1 · easy27. A 6-year-old boy presents with short stature (height <3rd percentile) and normal growth velocity of 4 cm/year. His bone age is 5 years, thyroid function is normal, and celiac se…
- USMLE Step 1 · medium28. A 38-year-old woman presents with progressive bifrontal headache and bitemporal hemianopsia. Vital signs show BP 158/94 mmHg, HR 88/min, RR 16/min, Temp 37.2°C. She denies recen…
- USMLE Step 1 · medium29. A 52-year-old woman presents with progressive headaches and bitemporal hemianopsia. Vital signs show BP 128/82, HR 78, RR 16, temp 37°C, SpO2 98%. MRI reveals a 28-mm sellar mas…
- USMLE Step 1 · medium30. A 45-year-old man presents 2 weeks after transsphenoidal pituitary surgery with polyuria (6 L/day) and polydipsia. Vital signs show HR 88/min, BP 128/82 mmHg, RR 16/min. Labs re…
- USMLE Step 1 · medium31. A 34-year-old woman presents with 6 months of amenorrhea and galactorrhea. Vital signs are normal (BP 118/76, HR 78, RR 14, Temp 98.6°F). Laboratory studies show elevated prolac…
- USMLE Step 1 · hard32. A 67-year-old man with a 3-month chronic cough presents with malaise and polyuria. Vital signs: BP 138/82, HR 88, RR 16, Temp 37.2°C, SpO2 98% on room air. Labs reveal serum cal…
- USMLE Step 1 · hard33. A 38-year-old man presents with sudden-onset weakness, high fever (39.2°C), and altered consciousness. Vital signs show BP 108/70 mmHg, HR 102/min, RR 20/min, SpO2 98% on room a…
- USMLE Step 1 · easy34. A 42-year-old woman presents with progressive frontal headaches, bitemporal hemianopsia, and secondary amenorrhea for 8 months. Vital signs: BP 128/82 mmHg, HR 76/min, RR 14/min…
- USMLE Step 1 · hard35. A 67-year-old man with treated hypothyroidism on levothyroxine 100 mcg daily presents with severe frontal headache, confusion, and bradycardia. Vital signs: BP 88/56, HR 48, RR…
- USMLE Step 1 · medium36. A 19-year-old woman underwent transsphenoidal pituitary surgery for a Rathke cleft cyst 1 month ago. She now presents with sudden-onset polydipsia, polyuria (6 L/day), and noctu…
- USMLE Step 1 · medium37. A 41-year-old man with recently diagnosed Cushing syndrome secondary to a pituitary corticotroph adenoma presents with hypertension (160/98 mmHg), tachycardia (102 bpm), and hyp…
- USMLE Step 1 · medium38. A 55-year-old woman with newly diagnosed acromegaly presents with hypertension (BP 152/94 mmHg), heart rate 88/min, and progressive coarsening of facial features over 2 years. M…
- USMLE Step 1 · hard39. A 62-year-old man with history of pituitary macroadenoma treated with transsphenoidal surgery 3 months ago presents with acute confusion, severe frontal headache, and nuchal rig…
- USMLE Step 1 · medium40. A 28-year-old man presents with erectile dysfunction, decreased libido, and progressive gynecomastia. He reports headaches and reduced peripheral vision. Laboratory studies show…
- USMLE Step 1 · medium41. A 34-year-old woman at 8 weeks gestation presents to the obstetric clinic with a known prolactinoma diagnosed 2 years ago, previously treated with bromocriptine resulting in tum…
- USMLE Step 1 · hard42. A 38-year-old woman with macroprolactinemia presents with secondary amenorrhea, galactorrhea, and decreased libido despite 6 months of cabergoline therapy. Vitals: BP 118/76, HR…
- USMLE Step 1 · hard43. A 52-year-old man who underwent pituitary adenectomy 2 years ago presents with progressive fatigue and confusion. Vital signs show BP 92/58 mmHg, HR 88 bpm, RR 16, temp 36.8°C.…
- USMLE Step 1 · medium44. A 45-year-old woman presents with progressive frontal headache, bitemporal hemianopsia, and amenorrhea for 8 months. Vital signs show BP 128/82 mmHg, HR 78/min, RR 14/min, tempe…
- USMLE Step 1 · medium45. A 39-year-old woman presents with progressive headaches and amenorrhea for 6 months. Vital signs: BP 118/76, HR 88, RR 16, Temp 37.2°C, SpO2 98%. MRI reveals a 1.8-cm nonfunctio…
- USMLE Step 1 · hard46. A 33-year-old woman presents with hypertension (BP 158/96), tachycardia (HR 102), and progressive central obesity with proximal muscle weakness. Laboratory studies show elevated…
- USMLE Step 1 · medium47. A 48-year-old woman presents with progressive shoe size increase, coarse facial features, and fasting hyperglycemia. Vital signs show BP 148/92 mmHg, HR 78/min, RR 16/min, tempe…
- USMLE Step 1 · medium48. A 27-year-old woman presents with infertility, oligomenorrhea, and galactorrhea. Vital signs: BP 118/76, HR 88, RR 16, Temp 37°C. Laboratory evaluation reveals serum prolactin 8…