Lipid Biochemistry USMLE Step 1 Practice Questions
102 board-style USMLE Step 1 questions in Biochemistry. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium49. A 38-year-old woman presents with recurrent eruptive xanthomas and lipemia retinalis. Vital signs show BP 145/92 mmHg, HR 88/min, RR 16/min, temp 37°C, SpO2 98%. Laboratory stud…
- USMLE Step 1 · medium50. A 41-year-old man with Type 2 diabetes presents with fatigue. Vital signs: BP 138/88 mmHg, HR 92 bpm, RR 16/min, Temp 37.0°C, SpO2 98% on room air. He denies chest pain. Labs sh…
- USMLE Step 1 · medium51. A 52-year-old woman on atorvastatin and ezetimibe for hypercholesterolemia presents with diffuse myalgias and dark urine. Vital signs: BP 128/82, HR 88, RR 16, Temp 37.2°C, SpO2…
- USMLE Step 1 · hard52. A 28-year-old man with familial hypertriglyceridemia presents with severe epigastric pain and recurrent acute pancreatitis. Vital signs show BP 128/82 mmHg, HR 102 bpm, RR 18/mi…
- USMLE Step 1 · hard53. A 62-year-old man with a history of myocardial infarction is found to have extremely low LDL cholesterol (25 mg/dL) and very low plasma levels of apolipoprotein B-containing lip…
- USMLE Step 1 · easy54. A 55-year-old woman with type 2 diabetes and hypertension presents with fatigue. Vital signs: BP 142/88 mmHg, HR 88/min, RR 16/min, temp 37°C, SpO2 98% on room air. Lipid panel…
- USMLE Step 1 · medium55. A 3-year-old girl from consanguineous parents presents to the emergency department with severe abdominal pain and recurrent pancreatitis. Vital signs show HR 120/min, BP 95/60,…
- USMLE Step 1 · hard56. A 28-year-old woman at 20 weeks gestation presents with severe epigastric pain and nausea. Vital signs show BP 128/82 mmHg, HR 102 bpm, RR 18, temp 37.2°C. Serum triglycerides a…
- USMLE Step 1 · medium57. A 45-year-old man with premature coronary artery disease (diagnosed at age 42) presents with yellow nodules on his elbows and Achilles tendons, plus corneal arcus. Vital signs:…
- USMLE Step 1 · medium58. A 55-year-old woman with cirrhosis from hepatitis C presents with easy bruising and epistaxis. Vital signs: BP 110/70, HR 88, RR 16, Temp 37°C, SpO2 98%. PT/INR is severely prol…
- USMLE Step 1 · medium59. A 42-year-old man with familial hypercholesterolemia presents with tendon xanthomas and premature coronary artery disease. Laboratory studies show LDL cholesterol of 520 mg/dL d…
- USMLE Step 1 · hard60. A 72-year-old man with chronic kidney disease (stage 4) presents with LDL cholesterol of 95 mg/dL on atorvastatin, but persistent hypertriglyceridemia (320 mg/dL) and very low H…
- USMLE Step 1 · medium61. A 19-year-old woman with history of recurrent pancreatitis is found to have fasting triglycerides of 650 mg/dL and chylomicrons visible on plasma electrophoresis. Her apoC-II le…
- USMLE Step 1 · medium62. A 55-year-old man develops acute coronary syndrome. His lipid panel shows total cholesterol of 220 mg/dL and LDL of 140 mg/dL, both moderate elevations. However, his Lp(a) level…
- USMLE Step 1 · hard63. A 34-year-old woman with family history of premature coronary artery disease presents with elevated lipids. Vital signs are normal; BP 118/76 mmHg, HR 72/min, RR 14/min. Laborat…
- USMLE Step 1 · hard64. A 51-year-old man with type 2 diabetes mellitus and metabolic syndrome presents with BP 148/92 mmHg, HR 88/min, and denies chest pain. Fasting laboratory studies show triglyceri…
- USMLE Step 1 · medium65. A 62-year-old man with a history of myocardial infarction is started on a statin for secondary prevention. After 4 weeks of therapy, his LDL decreases by 35%, but he develops my…
- USMLE Step 1 · hard66. A 3-year-old boy presents with failure to thrive, fatty stools, and cholestasis. Laboratory testing reveals severely elevated triglycerides (1200 mg/dL), very low cholesterol (8…
- USMLE Step 1 · medium67. A 38-year-old woman presenting for routine screening has a total cholesterol of 680 mg/dL and LDL of 520 mg/dL despite never taking statins. Physical examination reveals tendon…
- USMLE Step 1 · hard68. A 45-year-old man with type 2 diabetes presents with eruptive xanthomas on his elbows and palms. Vital signs: BP 148/92 mmHg, HR 88 bpm, RR 16, Temp 37°C, SpO2 98% RA. Labs show…
- USMLE Step 1 · medium69. A 50-year-old man with a family history of premature coronary artery disease presents for screening. Vital signs are BP 138/88 mmHg, HR 78/min, RR 16/min, temp 37°C, SpO2 98%. L…
- USMLE Step 1 · medium70. A 45-year-old man with a 20-year history of type 2 diabetes controlled with metformin presents with substernal chest pain. Vital signs: BP 142/88 mmHg, HR 92 bpm, RR 18, Temp 37…
- USMLE Step 1 · hard71. A 55-year-old man with type 2 diabetes and chronic kidney disease (GFR 35 mL/min/1.73m²) presents with nephrotic syndrome and bilateral lower extremity edema. Vital signs: BP 14…
- USMLE Step 1 · hard72. A 42-year-old woman with systemic lupus erythematosus on chronic prednisone develops acute chest pain. Vital signs show BP 145/92 mmHg, HR 102/min, RR 18/min, temp 37°C, SpO2 98…