Lipid Biochemistry USMLE Step 1 Practice Questions
102 board-style USMLE Step 1 questions in Biochemistry. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium73. A 68-year-old man with metabolic syndrome presents with BP 148/92 mmHg, HR 88/min, and fasting glucose 118 mg/dL despite metformin 1000 mg daily. Labs show triglycerides 280 mg/…
- USMLE Step 1 · hard74. A 3-year-old boy with consanguineous parents presents with failure to thrive, developmental delay, and progressive ataxia with nystagmus. Vital signs show HR 92/min, RR 20/min,…
- USMLE Step 1 · hard75. A 36-year-old man presents with recurrent acute pancreatitis, eruptive xanthomas, and lipemia retinalis. Vital signs show BP 138/88, HR 92, RR 18, temp 37°C, SpO₂ 98% on room ai…
- USMLE Step 1 · hard76. A 50-year-old woman on bile acid sequestrant therapy for hypercholesterolemia presents with fatigue and dyspnea. Vital signs: BP 142/88 mmHg, HR 92/min, RR 18/min, temp 37°C, Sp…
- USMLE Step 1 · hard77. A 6-year-old boy with failure to thrive presents with fat-soluble vitamin deficiencies (A, D, E, K), steatorrhea, and hepatomegaly. Vital signs show HR 102/min, BP 95/60 mmHg, a…
- USMLE Step 1 · medium78. A 28-year-old man presents with recurrent episodes of severe abdominal pain and pancreatitis. His triglyceride level is 1,800 mg/dL. He has earlobe creases and a family history…
- USMLE Step 1 · medium79. A 52-year-old man on atorvastatin 40 mg daily for hypercholesterolemia presents with acute myalgia and proximal muscle weakness. Vital signs: BP 138/82, HR 88, RR 16, Temp 37.2°…
- USMLE Step 1 · medium80. A 35-year-old woman with poorly controlled type 2 diabetes presents with acute abdominal pain and eruptive xanthomas. Vital signs: BP 138/82, HR 102, RR 18, Temp 37.2°C, SpO2 98…
- USMLE Step 1 · medium81. A 45-year-old man presents with premature coronary artery disease and xanthomas on his Achilles tendons. Laboratory studies show LDL cholesterol of 520 mg/dL despite a low-fat d…
- USMLE Step 1 · easy82. A 19-year-old college student presents with recurrent eruptive xanthomas and acute pancreatitis. Vital signs show HR 102, BP 128/76, RR 18, temp 37.2°C. Laboratory studies revea…
- USMLE Step 1 · hard83. A 28-year-old woman with Tangier disease presents with hepatosplenomegaly, lymphadenopathy, and progressive peripheral neuropathy. Vital signs show BP 118/76, HR 88, RR 16, Temp…
- USMLE Step 1 · hard84. A 52-year-old woman with primary biliary cirrhosis presents with xanthomas and jaundice. Vital signs: BP 128/82, HR 88, RR 16, Temp 37°C, SpO2 98%. Labs show alkaline phosphatas…
- USMLE Step 1 · medium85. A 3-year-old boy presents with failure to thrive and steatorrhea since infancy. Vital signs show HR 110, RR 22, normal BP and temperature. Laboratory studies reveal markedly ele…
- USMLE Step 1 · medium86. A 6-year-old boy with failure to thrive and chronic steatorrhea presents with BP 95/60, HR 98, RR 22, temp 37°C, SpO2 98%. He reports fat-soluble vitamin deficiencies (A, D, E,…
- USMLE Step 1 · hard87. A 42-year-old woman with systemic lupus erythematosus presents with recurrent bilateral lower extremity thromboses. Vital signs: BP 138/88 mmHg, HR 92/min, RR 18/min, temp 37.2°…
- USMLE Step 1 · hard88. A 55-year-old man with metabolic syndrome and prior MI at age 48 presents with elevated apolipoprotein B (142 mg/dL) despite normal LDL cholesterol (110 mg/L). Vitals: BP 148/92…
- USMLE Step 1 · medium89. A 19-year-old man presents with severe chest pain and is found to have an acute myocardial infarction. His fasting lipid panel shows total cholesterol of 680 mg/dL, triglyceride…
- USMLE Step 1 · hard90. A 35-year-old man with chronic kidney disease (stage 4, GFR 28 mL/min) presents with LDL cholesterol of 145 mg/dL despite a statin. His triglycerides are elevated at 280 mg/dL,…
- USMLE Step 1 · medium91. A 60-year-old woman with hypercholesterolemia taking atorvastatin presents with generalized myalgia and weakness for 3 days. Vital signs: BP 128/82, HR 92, RR 16, Temp 37.2°C, S…
- USMLE Step 1 · hard92. A 52-year-old man with type 2 diabetes and hypertension presents with BP 148/92 mmHg, HR 88/min, and truncal obesity. Laboratory studies show fasting glucose 156 mg/dL, triglyce…
- USMLE Step 1 · medium93. A 38-year-old woman with recurrent acute pancreatitis presents with milky serum and severe hypertriglyceridemia (1,800 mg/dL). Vital signs: BP 128/82 mmHg, HR 92/min, RR 18/min,…
- USMLE Step 1 · medium94. A 45-year-old man presents with xanthomas on his Achilles tendons and eyelids, along with premature coronary artery disease at age 42. Serum LDL cholesterol is 520 mg/dL despite…
- USMLE Step 1 · medium95. A 72-year-old man with gram-negative sepsis presents with hypotension (BP 78/52 mmHg), tachycardia (HR 118/min), tachypnea (RR 22/min), and fever (38.9°C). Laboratory findings r…
- USMLE Step 1 · medium96. A 21-year-old male participates in a nutrition study. Two hours after consuming a high-carbohydrate meal, he has elevated serum insulin levels (18 mIU/L; normal fasting <12). Vi…