Anemias USMLE Step 1 Practice Questions
57 board-style USMLE Step 1 questions in Hematology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard1. A 47-year-old woman with metastatic breast cancer who is undergoing chemotherapy comes to the physician for a follow-up exam. She reports extreme fatigue since beginning her che…
- USMLE Step 1 · medium2. A 21-year-old man comes to the physician because of a 3-day history of yellowing of his eyes. He has also noticed a decrease in his exercise capacity and gets quickly exhausted…
- USMLE Step 1 · hard3. A 21-year-old male college student presents with a 3-day history of jaundice, dyspnea on exertion, and fatigue. He reports a sore throat and malaise for the past 2 weeks. Vital…
- USMLE Step 1 · medium4. A 64-year-old man with a 12-year history of type 2 diabetes mellitus and hypertension presents to the clinic with progressive fatigue and dyspnea on exertion over the past 3 mon…
- USMLE Step 1 · medium5. A 51-year-old woman with rheumatoid arthritis on methotrexate presents with progressive fatigue and dyspnea on exertion. Vital signs show HR 98 bpm, BP 128/82 mmHg, RR 20/min, a…
- USMLE Step 1 · hard6. A 73-year-old man presents to clinic with a 3-month history of progressive dyspnea on exertion, fatigue, and bilateral lower extremity paresthesias. He has a past medical histor…
- USMLE Step 1 · medium7. A 19-year-old African American man with sickle cell disease presents to the emergency department with acute onset severe lower back and left flank pain. He reports the pain bega…
- USMLE Step 1 · hard8. A 31-year-old woman with systemic lupus erythematosus presents with dyspnea, chest pain, and confusion. Vital signs show BP 158/92 mmHg, HR 112/min, RR 22/min, temp 37.2°C, SpO2…
- USMLE Step 1 · medium9. A 56-year-old man with alcohol use disorder presents with dyspnea, glossitis, and paresthesias. Hemoglobin is 9.1 g/dL with MCV 110 fL. Serum B12 is 180 pg/mL (normal >200), and…
- USMLE Step 1 · easy10. A 42-year-old woman presents to clinic with a 3-month history of progressive fatigue and dyspnea on exertion. She reports heavy menstrual bleeding for the past decade that has w…
- USMLE Step 1 · medium11. A 28-year-old woman of Mediterranean descent presents with mild anemia (hemoglobin 10.2 g/dL), microcytia (MCV 72 fL), and normal iron stores. Serum ferritin is elevated at 145…
- USMLE Step 1 · medium12. A 67-year-old man with chronic kidney disease (creatinine 3.2 mg/dL) presents with progressive dyspnea and fatigue. Vital signs show BP 148/92 mmHg, HR 102/min, RR 22/min, SpO2…
- USMLE Step 1 · medium13. A 34-year-old woman presents to the emergency department with a 3-day history of fatigue, dyspnea on exertion, and dark urine. She reports a sore throat and low-grade fever 2 we…
- USMLE Step 1 · medium14. A 61-year-old woman develops acute dyspnea, fever, and hypoxemia within 2 hours of plasma transfusion. Vital signs show BP 128/82 mmHg, HR 118 bpm, RR 28/min, temperature 38.5°C…
- USMLE Step 1 · medium15. A 37-year-old woman with iron deficiency anemia (hemoglobin 6.2 g/dL) receives a packed red blood cell transfusion. Thirty minutes later, she develops fever (38.9°C), chills, an…
- USMLE Step 1 · medium16. A 54-year-old man with a history of peptic ulcer disease receives a packed red blood cell transfusion following acute gastrointestinal bleeding. Within minutes, he develops feve…
- USMLE Step 1 · medium17. A 4 year old girl is brought to the emergency department with reduced urine output and pallor 5 days after an episode of bloody diarrhea at a petting zoo. Laboratory studies sho…
- USMLE Step 1 · medium18. A 34-year-old pregnant woman with alcohol use disorder presents with fatigue and glossitis. Vital signs show BP 118/76 mmHg, HR 88/min, RR 16/min, temperature 37.2°C, and SpO2 9…
- USMLE Step 1 · easy19. A 71-year-old woman presents with progressive fatigue, paresthesias, and gait imbalance over 3 months. Vital signs: BP 128/76, HR 88, RR 16, temp 37°C, SpO2 98%. Examination rev…
- USMLE Step 1 · hard20. A 29 year old woman with sickle cell disease presents with sudden severe fatigue after her child had a viral illness with a slapped cheek rash. Laboratory studies show hemoglobi…
- USMLE Step 1 · medium21. A 28 year old woman presents with fatigue, frequent nosebleeds, and recurrent infections. She recently completed chloramphenicol therapy abroad. Examination shows scattered pete…
- USMLE Step 1 · medium22. A 21-year-old college student presents with fatigue and dark urine one week after recovering from atypical pneumonia. He reports Raynaud phenomenon with painful, pale fingers in…
- USMLE Step 1 · medium23. A 39-year-old woman with systemic lupus erythematosus on hydroxychloroquine presents with progressive fatigue and jaundice. Vital signs show BP 118/76, HR 102, RR 18, temperatur…
- USMLE Step 1 · hard24. A 34-year-old man presents with episodic dark urine, fatigue, and abdominal pain. Vital signs show BP 118/76, HR 92, RR 16, temp 37.2°C, SpO2 98%. Laboratory studies reveal intr…