Anemias USMLE Step 1 Practice Question
A 34-year-old pregnant woman with alcohol use disorder presents with fatigue and glossitis. Vital signs show BP 118/76 mmHg, HR 88/min, RR 16/min, temperature 37.2°C, and SpO2 98% on room air. Laboratory studies reveal hemoglobin 9.4 g/dL, MCV 110 fL, hypersegmented neutrophils, elevated homocysteine, and normal methylmalonic acid. Intrinsic factor antibodies are negative. She denies neurologic symptoms. Which of the following is the most likely diagnosis?
Answer choices
- ACopper deficiency
- BWarm autoimmune hemolytic anemia
- CFolate deficiencyCorrect answer
- DIron deficiency anemia
- EVitamin B12 deficiency
- FThiamine deficiency
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