Anemias USMLE Step 1 Practice Question
A 28-year-old woman of Mediterranean descent presents with mild anemia (hemoglobin 10.2 g/dL), microcytia (MCV 72 fL), and normal iron stores. Serum ferritin is elevated at 145 ng/mL (normal <150). Hemoglobin electrophoresis shows elevated hemoglobin A2 (3.8%) and normal fetal hemoglobin. Which of the following is the most likely diagnosis?
Answer choices
- ASickle cell trait
- Bβ-Thalassemia traitCorrect answer
- CIron deficiency anemia
- DHemoglobin E disease
- Eα-Thalassemia trait
- FAnemia of chronic disease
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