Adrenal Disorders USMLE Step 1 Practice Questions
56 board-style USMLE Step 1 questions in Endocrinology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium25. A 28-year-old woman presents with a 2-week history of progressive fatigue, myalgias, and orthostatic lightheadedness. She was recently diagnosed with primary adrenal insufficien…
- USMLE Step 1 · medium26. A 42-year-old man on warfarin for atrial fibrillation presents to the emergency department with acute onset severe left flank pain, fever (38.9°C), and hypotension (BP 88/54 mmH…
- USMLE Step 1 · hard27. A 35-year-old woman with newly diagnosed hypertension and hypokalemia undergoes screening. Serum aldosterone is 18 ng/dL with plasma renin activity of 0.8 ng/mL/hr. Aldosterone-…
- USMLE Step 1 · easy28. A 52-year-old woman presents with progressive weakness, fatigue, and darkening skin pigmentation despite minimal sun exposure. Vital signs reveal hypotension (88/52 mmHg), heart…
- USMLE Step 1 · medium29. A 38-year-old man presents to the emergency department with a 3-month history of episodic severe headaches, diaphoresis, and palpitations. His wife notes he has become increasin…
- USMLE Step 1 · medium30. A 45-year-old woman presents with progressive hypertension and muscle weakness. Vital signs show BP 168/102 mmHg, HR 88 bpm, RR 14, temp 37°C, SpO2 98%. Laboratory studies revea…
- USMLE Step 1 · hard31. A 34-year-old woman with autoimmune Addison disease on hydrocortisone and fludrocortisone presents with acute severe abdominal pain, confusion, and hypotension (BP 88/52, HR 118…
- USMLE Step 1 · medium32. A 55-year-old man with a 10-year history of hypertension treated with lisinopril presents to the emergency department with acute onset palpitations, tremor, and profuse diaphore…
- USMLE Step 1 · medium33. A 6-year-old boy presents with accelerated linear growth, pubic hair development, and genital enlargement. Vital signs show BP 128/82 mmHg, HR 92 bpm, RR 18, temp 37°C, SpO2 98%…
- USMLE Step 1 · hard34. A 42-year-old woman presents to clinic with a 6-month history of progressive fatigue, weight gain, and cold intolerance. She denies easy bruising, proximal weakness, or skin cha…
- USMLE Step 1 · easy35. A 28-year-old woman with autoimmune thyroiditis presents with progressive fatigue, dizziness, and orthostatic hypotension. Vital signs show BP 92/58 mmHg, HR 102 bpm, RR 18, tem…
- USMLE Step 1 · medium36. A 52-year-old man presents with acute onset severe headache, profuse diaphoresis, palpitations, and blood pressure of 185/110 mmHg. His symptoms are episodic, lasting 30-60 minu…
- USMLE Step 1 · medium37. A 38-year-old man presents with newly diagnosed hypertension (BP 168/104 mmHg, HR 88/min) and muscle weakness. Laboratory studies reveal hypokalemia (K+ 2.9 mEq/L), elevated pla…
- USMLE Step 1 · easy38. A 45-year-old woman presents with progressive proximal muscle weakness, purple striae, central obesity, and hypertension. Laboratory studies show elevated 24-hour urinary free c…
- USMLE Step 1 · hard39. A 70-year-old man with metastatic lung adenocarcinoma presents with progressive fatigue, anorexia, and weight loss. Vital signs show BP 92/58 mmHg, HR 104 bpm, RR 16, temperatur…
- USMLE Step 1 · medium40. A 17-year-old boy presents with mucosal neuromas on his lips and tongue, marfanoid habitus, and chronic constipation. Vital signs are BP 155/92 mmHg, HR 98 bpm, RR 16, Temp 37°C…
- USMLE Step 1 · medium41. A 29-year-old woman with medullary thyroid carcinoma presents with hypertension (BP 158/96 mmHg), tachycardia (HR 104/min), and anxiety. Laboratory studies reveal elevated 24-ho…
- USMLE Step 1 · medium42. A 36-year-old man with a prolactin-secreting pituitary adenoma presents with recurrent nephrolithiasis, recurrent peptic ulcers, and diarrhea. Vital signs: BP 158/95 mmHg, HR 88…
- USMLE Step 1 · hard43. A 33-year-old woman presents with progressive fatigue, nausea, 8-kg weight loss, and orthostatic dizziness. Vital signs show BP 98/62 mmHg, HR 102 bpm, RR 18/min, temp 36.8°C, S…
- USMLE Step 1 · medium44. A 50-year-old woman with hypertension (BP 168/104 mmHg, HR 88/min) is found to have a 2-cm adrenal adenoma on CT imaging producing elevated aldosterone (28 ng/dL; normal <16). L…
- USMLE Step 1 · medium45. A 45-year-old woman with a CT-confirmed adrenal pheochromocytoma (8 cm mass with high attenuation) is scheduled for surgical resection. Currently BP 128/82 mmHg, HR 88 bpm, but…
- USMLE Step 1 · medium46. A 40-year-old man presents with recurrent episodes of severe headache, palpitations, and diaphoresis. Current vital signs show BP 168/104 mmHg, HR 118/min, RR 16/min, and temper…
- USMLE Step 1 · easy47. A 34-year-old woman presents with recurrent episodes of pounding headache, diaphoresis, and palpitations lasting 20-30 minutes. During an acute episode, vital signs show BP 210/…
- USMLE Step 1 · hard48. A 16-year-old 46,XY phenotypic female presents with primary amenorrhea, absent breast development, and sparse pubic hair. Vital signs show BP 148/92 mmHg, HR 88/min, RR 16/min.…