Adrenal Disorders USMLE Step 1 Practice Question
A 38-year-old man presents with newly diagnosed hypertension (BP 168/104 mmHg, HR 88/min) and muscle weakness. Laboratory studies reveal hypokalemia (K+ 2.9 mEq/L), elevated plasma aldosterone (22 ng/dL), and suppressed plasma renin activity (0.3 ng/mL/hr; normal 0.5-3.5). Serum sodium is normal. Adrenal CT demonstrates a 1.8 cm left adrenal nodule with low attenuation. Which of the following is the most likely diagnosis?
Answer choices
- ACushing syndrome
- BPrimary hyperaldosteronism (aldosterone-producing adenoma)Correct answer
- CAdrenal carcinoma
- DSecondary hyperaldosteronism
- EPheochromocytoma
- FRenovascular hypertension with secondary hyperreninism
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