Adrenal Disorders USMLE Step 1 Practice Question
A 40-year-old man presents with recurrent episodes of severe headache, palpitations, and diaphoresis. Current vital signs show BP 168/104 mmHg, HR 118/min, RR 16/min, and temperature 37°C. He denies chest pain or dyspnea. Laboratory studies reveal elevated plasma free metanephrines at 4.2 times the upper limit of normal. His physician suspects a catecholamine-secreting tumor. Which of the following tests is most appropriate to confirm the diagnosis and localize the lesion?
Answer choices
- ASerum aldosterone to renin ratio
- BSerum IGF 1 concentration
- CPlasma free metanephrinesCorrect answer
- DCosyntropin stimulation test
- ELow dose dexamethasone suppression test
- F24-hour urine catecholamine collection
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