Neuromuscular Disorders USMLE Step 1 Practice Questions
64 board-style USMLE Step 1 questions in Neurology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · easy25. A 44-year-old woman presents with nighttime numbness and tingling in the thumb, index finger, middle finger, and lateral half of the ring finger that awakens her from sleep. Vit…
- USMLE Step 1 · easy26. A 25-year-old man develops right foot drop and difficulty dorsiflexing the foot after wearing a tight leg cast for 5 days. Vital signs are stable (BP 120/80, HR 78, RR 16). Exam…
- USMLE Step 1 · easy27. A 33-year-old man with a history of heavy alcohol use falls asleep in a chair with his arm draped over the backrest. Upon awakening, he is unable to extend his wrist and fingers…
- USMLE Step 1 · medium28. A 47-year-old woman presents with a 3-week history of progressive weight loss and palpable purpura on her lower extremities. She develops abrupt left wrist drop followed 2 weeks…
- USMLE Step 1 · hard29. A 64-year-old man with poorly controlled type 2 diabetes (HbA1c 9.2%) presents with severe pain in the right thigh progressing to weakness of hip flexion and knee extension over…
- USMLE Step 1 · easy30. A 59-year-old man with poorly controlled type 2 diabetes mellitus (HbA1c 9.2%) presents with a 1-year history of progressive burning pain and numbness in both feet. Vital signs:…
- USMLE Step 1 · medium31. A 15-year-old boy presents with progressive difficulty running and recurrent ankle sprains over the past year. Vital signs are normal (BP 118/76, HR 82, RR 16, Temp 98.6°F, SpO2…
- USMLE Step 1 · hard32. A 49-year-old man presents with 4 months of progressive symmetric weakness and paresthesias in his arms and legs. Vital signs: BP 138/82, HR 88, RR 16, Temp 37.2°C, SpO2 98%. De…
- USMLE Step 1 · medium33. A 31-year-old woman presents with acute ascending paralysis and areflexia. Vital signs show HR 92/min, BP 138/84 mmHg, RR 18/min, temperature 37.2°C, SpO2 98% on room air. Cereb…
- USMLE Step 1 · easy34. A 27-year-old man presents with progressive bilateral leg weakness and paresthesias over 3 days following diarrheal illness 2 weeks prior. Vital signs: BP 138/82, HR 98, RR 20,…
- USMLE Step 1 · hard35. A 72-year-old man presents with slowly progressive proximal weakness over 2 years, affecting stair climbing and grip strength. Vital signs: BP 138/82, HR 88, RR 16, Temp 37.2°C,…
- USMLE Step 1 · medium36. A 51-year-old woman presents with progressive proximal muscle weakness and difficulty rising from a chair over 3 months. Vital signs show BP 128/82, HR 92, RR 16, temp 37.2°C, S…
- USMLE Step 1 · medium37. A 46-year-old woman presents with 3 months of progressive proximal muscle weakness affecting stair climbing and hair combing. Vital signs: BP 128/82, HR 92, RR 16, Temp 37°C, Sp…
- USMLE Step 1 · medium38. A 34-year-old man presents with difficulty releasing his grip after handshaking. He reports early frontal balding and recent cataracts. Vital signs are stable: BP 128/82, HR 78,…
- USMLE Step 1 · medium39. A 17-year-old boy presents with 2-year history of progressive proximal muscle weakness affecting hip and shoulder girdles. He ambulates independently but reports difficulty risi…
- USMLE Step 1 · easy40. A 5-year-old boy presents with progressive difficulty climbing stairs and frequent falls over the past 6 months. He uses his hands to push himself upright from the floor (Gowers…
- USMLE Step 1 · medium41. A 6-month-old boy presents with developmental delay and inability to sit unsupported. Vital signs show HR 110 bpm, RR 28, temp 37°C, SpO2 98%. On exam, he has marked hypotonia,…
- USMLE Step 1 · medium42. A 61-year-old woman with amyotrophic lateral sclerosis presents with progressive lower extremity weakness over 8 months. Vital signs: BP 128/76, HR 88, RR 18, SpO2 98% on room a…
- USMLE Step 1 · easy43. A 58-year-old man presents with 8 months of progressive weakness in his hands and legs. Vital signs: BP 128/76, HR 82, RR 16, temp 37°C, SpO2 98%. Examination reveals muscle atr…
- USMLE Step 1 · medium44. A 52-year-old man presents to the emergency department with jaw stiffness and severe generalized muscle spasms 1 week after a puncture wound from a rusty nail. Vital signs show…
- USMLE Step 1 · medium45. A 37-year-old woman presents 18 hours after consuming improperly canned vegetables with blurred vision, dysphagia, and progressive descending symmetric paralysis. Vital signs: B…
- USMLE Step 1 · medium46. A 4-month-old boy presents with poor feeding, weak cry, constipation, and progressive generalized hypotonia over the past week. Parents report recent honey ingestion. Vital sign…
- USMLE Step 1 · medium47. A 63-year-old man presents with a 3-month history of difficulty rising from a chair and dry mouth. Vital signs: BP 142/88 mmHg, HR 88/min, RR 16/min, temp 37°C, SpO2 98% on room…
- USMLE Step 1 · medium48. A 41-year-old woman presents with progressive ptosis and intermittent diplopia worsening throughout the day. She reports difficulty sustaining arm elevation above her head after…