Neuromuscular Disorders USMLE Step 1 Practice Question
A 64-year-old man with poorly controlled type 2 diabetes (HbA1c 9.2%) presents with severe pain in the right thigh progressing to weakness of hip flexion and knee extension over 4 weeks. Vital signs show BP 148/92, HR 88, RR 16, temp 37.1°C. Patellar reflex is diminished on the right; ankle reflexes are normal. Strength testing reveals hip flexor and quadriceps weakness (4/5). Electromyography shows denervation in the right femoral nerve distribution. Which diagnosis is most likely?
Answer choices
- AGuillain-Barré syndrome
- BDiabetic lumbosacral radiculoplexus neuropathyCorrect answer
- CCauda equina compression
- DLambert-Eaton syndrome
- EMyotonic dystrophy
- FFemoral nerve compression from retroperitoneal hematoma
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