Acute Kidney Injury USMLE Step 1 Practice Questions
56 board-style USMLE Step 1 questions in Nephrology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard25. A 52-year-old woman with a history of recurrent urinary tract infections presents to the emergency department with concern for acute kidney injury. She started trimethoprim-sulf…
- USMLE Step 1 · hard26. A 68-year-old man with newly diagnosed multiple myeloma presents to the emergency department with fatigue, nausea, and a 3-day history of decreased urine output. He started bort…
- USMLE Step 1 · hard27. A 35-year-old man is brought to the emergency department 18 hours after being trapped under a collapsed scaffold at a construction site. He reports severe pain in both legs and…
- USMLE Step 1 · medium28. A 28-year-old woman presents 5 days after starting ibuprofen for menstrual cramps with fever (39.2°C), diffuse maculopapular rash, and arthralgias. Vital signs: HR 102/min, BP 1…
- USMLE Step 1 · medium29. A 62-year-old man with sepsis from pneumonia receives aggressive IV fluid resuscitation. Despite 5 liters given, his blood pressure remains 88/52 mmHg, urine output is 0.2 mL/kg…
- USMLE Step 1 · medium30. A 72-year-old man with a history of hypertension, type 2 diabetes mellitus, and chronic kidney disease (baseline creatinine 1.4 mg/dL) undergoes cardiac catheterization via femo…
- USMLE Step 1 · medium31. A 68 year old woman is admitted for vomiting and profuse diarrhea for 3 days. She is dizzy on standing and has dry mucous membranes. BUN is 46 mg/dL and creatinine is 1.6 mg/dL.…
- USMLE Step 1 · medium32. A 74 year old man presents with suprapubic discomfort, nocturia, and weak urinary stream. Over the last day he has had difficulty voiding. Laboratory studies show rising BUN and…
- USMLE Step 1 · hard33. A 46-year-old woman presents with acute onset hematuria and rapidly rising creatinine (baseline 0.8 mg/dL, now 3.2 mg/dL). Vital signs: BP 156/94 mmHg, HR 92, RR 18, temp 37.2°C…
- USMLE Step 1 · hard34. A 2-day-old male presents with severe generalized edema and oliguria. Vital signs show BP 65/42 mmHg, HR 145/min, RR 38/min, and temperature 37.2°C. Urinalysis reveals massive p…
- USMLE Step 1 · hard35. A 78-year-old woman with poor oral intake for 3 days presents with hypotension (BP 88/52), tachycardia (HR 110), and oliguria. Serum creatinine is 2.8 mg/dL (baseline 0.9), BUN…
- USMLE Step 1 · medium36. A 5-year-old girl develops bloody diarrhea after consuming undercooked beef at a picnic. Three days later, she presents with pallor, decreased urine output, and petechiae. Vital…
- USMLE Step 1 · medium37. A 10-year-old boy presents with a 3-day history of abdominal pain, arthralgia, and a palpable purpuric rash on the lower extremities. Vital signs show BP 128/82 mmHg, HR 98/min,…
- USMLE Step 1 · hard38. A 68-year-old man with hypertension presents with acute dyspnea and orthopnea. Vital signs: BP 168/95 mmHg, HR 110/min, RR 22/min, SpO2 88% on room air. He takes lisinopril but…
- USMLE Step 1 · hard39. A 58-year-old man with sepsis presents with acute kidney injury. Vital signs show BP 92/58 mmHg, HR 118/min, RR 22/min, temperature 39.2°C, and SpO2 98% on room air. Serum creat…
- USMLE Step 1 · medium40. A 70-year-old man with acute intracranial hemorrhage receives intravenous mannitol. Within hours, he develops worsening dyspnea and bibasilar crackles. Vital signs show BP 168/9…
- USMLE Step 1 · hard41. A 35-year-old man with membranous nephropathy presents with sudden left flank pain and gross hematuria. Vital signs show BP 158/96 mmHg, HR 102/min, RR 18/min, temperature 37.2°…
- USMLE Step 1 · medium42. A 67-year-old man with diffuse atherosclerosis and poorly controlled hypertension despite amlodipine, hydrochlorothiazide, and metoprolol presents with acute dyspnea and fatigue…
- USMLE Step 1 · medium43. A 58 year old woman with long standing diabetes mellitus and chronic back pain presents with gross hematuria. She reports daily use of multiple over the counter pain medications…
- USMLE Step 1 · easy44. A 29 year old woman presents with fever, chills, nausea, and left flank pain. She has a history of recurrent urinary tract infections. Temperature is 39.1 C and costovertebral a…
- USMLE Step 1 · easy45. A 42-year-old woman presents with fever (38.9°C), diffuse maculopapular rash, and bilateral flank pain 5 days after starting trimethoprim-sulfamethoxazole for a skin infection.…
- USMLE Step 1 · medium46. A 58-year-old woman hospitalized with infective endocarditis receives intravenous gentamicin therapy. After 7 days, she develops oliguria with BP 128/82 mmHg, HR 92/min, and SpO…
- USMLE Step 1 · easy47. A 71 year old man is admitted for septic shock due to pneumonia. He remains hypotensive for several hours despite fluid resuscitation. Two days later his serum creatinine rises…
- USMLE Step 1 · medium48. A 24 year old woman with photosensitive rash and joint pain presents with edema, hypertension, and cola colored urine. Laboratory studies show positive anti double stranded DNA…