Acute Kidney Injury USMLE Step 1 Practice Question
A 28-year-old woman presents 5 days after starting ibuprofen for menstrual cramps with fever (39.2°C), diffuse maculopapular rash, and arthralgias. Vital signs: HR 102/min, BP 128/76 mmHg, RR 18/min, SpO2 98% on room air. Serum creatinine is 2.8 mg/dL (baseline 0.8), eosinophils 12%, and urinalysis shows WBC casts and eosinophiluria. Chest imaging is unremarkable. Which of the following is the most likely diagnosis?
Answer choices
- AAcute interstitial nephritisCorrect answer
- BAcute tubular necrosis
- CDrug-induced systemic lupus erythematosus
- DIgA nephropathy
- EPrerenal azotemia from dehydration
- FAcute glomerulonephritis from post-streptococcal infection
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