Acute Kidney Injury USMLE Step 1 Practice Question
A 42-year-old woman presents with fever (38.9°C), diffuse maculopapular rash, and bilateral flank pain 5 days after starting trimethoprim-sulfamethoxazole for a skin infection. Vital signs show HR 102/min, BP 138/88 mmHg, RR 18/min. Serum creatinine is 2.8 mg/dL (baseline 0.9), and urinalysis reveals pyuria, white blood cell casts, and eosinophiluria. Notably, no proteinuria or hematuria is present. Which of the following is the most likely diagnosis?
Answer choices
- ANephrolithiasis
- BPapillary necrosis
- CPoststreptococcal glomerulonephritis
- DAcute tubular necrosis
- EAcute interstitial nephritisCorrect answer
- FIgA nephropathy
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