Acute Kidney Injury USMLE Step 1 Practice Question
A 67-year-old man with diffuse atherosclerosis and poorly controlled hypertension despite amlodipine, hydrochlorothiazide, and metoprolol presents with acute dyspnea and fatigue. Vital signs: BP 168/98 mmHg, HR 92/min, RR 18/min, SpO2 98%. After lisinopril initiation, serum creatinine rises from 1.1 to 3.2 mg/dL within 5 days. Physical examination reveals a systolic abdominal bruit; no peripheral edema noted. Which diagnosis best explains his acute kidney injury?
Answer choices
- AMinimal change disease
- BAcute interstitial nephritis
- CRenal artery stenosisCorrect answer
- DAcute tubular necrosis
- EAutosomal recessive polycystic kidney disease
- FMembranoproliferative glomerulonephritis
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