Virology USMLE Step 1 Practice Questions
51 board-style USMLE Step 1 questions in Microbiology/Immunology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 Ā· hard25. A 62-year-old man with poorly controlled type 2 diabetes mellitus (HbA1c 9.2%) presents to the hospital with a 3-week history of progressive dyspnea, fever, and hemoptysis. He lā¦
- USMLE Step 1 Ā· easy26. A 3-year-old boy presents with sudden onset of fever, irritability, and neck stiffness. Vital signs show temperature 39.2°C, heart rate 118/min, blood pressure 102/68 mmHg, andā¦
- USMLE Step 1 Ā· medium27. A 34-year-old woman presents to clinic with a 3-day history of fever (39.2°C), severe myalgia, and a maculopapular rash involving her palms and soles. She returned from a hikingā¦
- USMLE Step 1 Ā· hard28. A 24-year-old man presents with acute hepatitis. Vital signs: BP 118/76 mmHg, HR 92/min, RR 16/min, Temp 38.2°C, SpO2 98% on room air. Laboratory studies reveal elevated ALT (84ā¦
- USMLE Step 1 Ā· medium29. A 39-year-old man with advanced HIV infection (CD4+ count 45 cells/μL) presents with 2 weeks of progressive dyspnea and nonproductive cough. Vital signs show BP 118/76 mmHg, HRā¦
- USMLE Step 1 Ā· medium30. A 28-year-old man bitten on the hand by a stray bat while camping does not seek immediate medical care. Three weeks later, he presents with fever (38.5°C), anxiety, hydrophobia,ā¦
- USMLE Step 1 Ā· medium31. A 17-year-old boy presents with fever (38.9°C), pharyngitis, and posterior cervical lymphadenopathy. Vital signs show HR 102 bpm, BP 118/76 mmHg, RR 18/min, SpO2 98% on room airā¦
- USMLE Step 1 Ā· hard32. A 36 year old man with untreated HIV infection develops progressive visual changes, weakness, and difficulty speaking over several weeks. MRI of the brain shows multiple asymmetā¦
- USMLE Step 1 Ā· medium33. A 39-year-old man with advanced HIV infection (CD4 count 45 cells/μL) presents with painful oral vesicles and fever (38.2°C). Despite 10 days of intravenous acyclovir (10 mg/kgā¦
- USMLE Step 1 Ā· medium34. A 3-month-old infant is hospitalized in winter with bronchiolitis. Vital signs show temperature 38.2°C, heart rate 160/min, respiratory rate 58/min, and oxygen saturation 88% onā¦
- USMLE Step 1 Ā· medium35. A 67-year-old man with hypertension presents with fever (38.5°C), cough, and myalgias for 3 days despite receiving the influenza vaccine 2 months ago. Vital signs show HR 98/minā¦
- USMLE Step 1 Ā· easy36. A 30-year-old pregnant woman at 16 weeks gestation presents for travel counseling before visiting Central America. She has vital signs: BP 118/76, HR 82, RR 16, Temp 37°C, SpO2ā¦
- USMLE Step 1 Ā· medium37. A 31-year-old man enrolled in an HIV drug trial receives a CCR5 antagonist. He presents with fever (38.2°C), tachycardia (102 bpm), and fatigue. Recent CD4 count is 450 cells/μLā¦
- USMLE Step 1 Ā· medium38. A 38-year-old woman with chronic hepatitis B (HBsAg positive, HBV DNA 2.5 Ć 10ā¶ IU/mL) is started on a cytokine to enhance antiviral immunity. Three weeks later, she presents wiā¦
- USMLE Step 1 Ā· medium39. A 58-year-old man presents with rapidly progressive dementia, ataxia, and myoclonus over three months. Vital signs show BP 128/82, HR 88, RR 16, temp 37.2°C, SpO2 98%. Electroenā¦
- USMLE Step 1 Ā· medium40. A 32-year-old man presents with fever (38.5°C), fatigue, and generalized lymphadenopathy. CD4+ count is 450 cells/μL with detectable viral load of 85,000 copies/mL. He denies opā¦
- USMLE Step 1 Ā· easy41. A hospital epidemiologist investigates a viral outbreak on the oncology ward affecting 12 immunocompromised patients presenting with fever (38.5°C), cough, and diarrhea. Vital sā¦
- USMLE Step 1 Ā· medium42. A 70-year-old man presents with fever (39.2°C), cough, and dyspnea during a sudden influenza pandemic caused by a novel strain. Vital signs show HR 108, RR 22, BP 138/82, SpO2 9ā¦
- USMLE Step 1 Ā· easy43. A 15-year-old boy presents with fever (39.2°C), severe pharyngitis, and posterior cervical lymphadenopathy. Vital signs show HR 102/min, BP 118/76 mmHg, RR 18/min, and SpO2 98%ā¦
- USMLE Step 1 Ā· medium44. A 20-year-old college student presents with sore throat, fever, and fatigue for 5 days. Vital signs: temperature 38.5°C, HR 92/min, BP 118/76, RR 16/min, SpO2 98%. Exam revealsā¦
- USMLE Step 1 Ā· medium45. A 19-year-old army recruit presents with jaundice and malaise. Vital signs show BP 118/76 mmHg, HR 88 bpm, RR 16/min, temperature 37.2°C, SpO2 98% on room air. Serum analysis reā¦
- USMLE Step 1 Ā· medium46. A 7-month-old child presents with a 4-day history of fever, deepening cough, and dyspnea. A chest x-ray film shows multiple interstitial infiltrates and hyperinflation of the luā¦
- USMLE Step 1 Ā· medium47. A 25-year-old Afghani immigrant presents with a confluent maculopapular rash that began on her face then spread downward over her trunk. She states that 3 days ago she started hā¦
- USMLE Step 1 Ā· medium48. About a month after being bitten by a bat, a man develops an influenza-like illness. He subsequently develops striking mood changes, pharyngeal spasms with drooling, and seizureā¦