Virology USMLE Step 1 Practice Question
A 20-year-old college student presents with sore throat, fever, and fatigue for 5 days. Vital signs: temperature 38.5°C, HR 92/min, BP 118/76, RR 16/min, SpO2 98%. Exam reveals cervical lymphadenopathy and mild hepatomegaly. Laboratory studies show elevated transaminases (ALT 78 U/L) and negative heterophile antibody test. Monospot is also negative. No rash is noted. Microscopic examination of infected fibroblasts would be expected to reveal which of the following?
Answer choices
- AStaining with India ink
- BA giant nucleus surrounded by a clear zoneCorrect answer
- CConidia and septate hyphae
- DAn enlarged nucleus with peripherally displaced chromatin
- EIntranuclear acidophilic inclusion bodies
- FIntracytoplasmic eosinophilic inclusion bodies
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