Mycology/Parasitology USMLE Step 1 Practice Questions
55 board-style USMLE Step 1 questions in Microbiology/Immunology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · easy1. A 6-year-old boy from rural Peru presents with fatigue, abdominal distension, and intermittent diarrhea for 6 months. Stool microscopy reveals 44-76 μm oval ova with a mucoid pl…
- USMLE Step 1 · medium2. A 55-year-old man with type 2 diabetes and poor glucose control presents with a black, necrotic lesion on his hard palate that extends into surrounding tissues. He reports rapid…
- USMLE Step 1 · medium3. A 28-year-old immunocompetent man from Ohio develops fever, myalgias, and a dry cough that progresses over 4 weeks. He works in construction and was recently exposed to bird dro…
- USMLE Step 1 · medium4. A 32-year-old woman presents with a 3-week history of progressive dyspnea, fever, and chest discomfort. Chest X-ray shows bilateral interstitial infiltrates. She recently adopte…
- USMLE Step 1 · hard5. A 7-year-old boy from Ghana presents with nodules on his shins, back, and elbows. He also complains of nerve pain along his forearms. Examination reveals areas of decreased sens…
- USMLE Step 1 · medium6. A 41-year-old man with a history of tuberculosis presents with cough and hemoptysis. Sputum smear shows acid-fast bacilli. He also has watery diarrhea and thrush. CD4 count is 8…
- USMLE Step 1 · medium7. A 3-year-old girl from rural Brazil presents with fever (38.5°C), difficulty swallowing, and painful ulcerated lesions in the oral mucosa. Physical examination reveals cervical…
- USMLE Step 1 · medium8. A 52-year-old immunocompromised patient on long-term corticosteroids presents with progressive dyspnea and productive cough. Vital signs show BP 128/76, HR 102, RR 22, Temp 38.2…
- USMLE Step 1 · medium9. A 35-year-old woman presents with a painful ulcer on her foot following a rose thorn prick while gardening. Over several weeks, nodular lesions have spread in a linear pattern a…
- USMLE Step 1 · medium10. A 6-year-old child from West Africa presents with itching and a painless subcutaneous nodule over the shin. On examination, a small hole is noted at the center of the nodule, wi…
- USMLE Step 1 · easy11. A 45-year-old man with advanced HIV (CD4 count 38/μL) presents with severe headache, fever (39.2°C), and neck stiffness. Vital signs show BP 118/76, HR 94, RR 18, SpO2 98% on ro…
- USMLE Step 1 · medium12. A 28-year-old man recently returned from caving in Arizona presents with a 2-week history of productive cough and fever (38.5°C). Vital signs show HR 102 bpm, RR 20/min, BP 118/…
- USMLE Step 1 · medium13. A 32-year-old woman with poorly controlled diabetes (HbA1c 11.2%) presents with progressive vision loss and orbital pain. Vital signs: BP 148/92, HR 102, RR 20, Temp 38.1°C, SpO…
- USMLE Step 1 · hard14. A 28-year-old male returns from rural Brazil with unilateral periorbital edema (Romana sign), fever (38.5°C), tachycardia (102 bpm), and generalized lymphadenopathy. Thin blood…
- USMLE Step 1 · hard15. A 35-year-old man with intravenous drug use history presents with persistent fever (39.2°C), headache, and neck stiffness for 2 weeks. Vital signs: HR 102, BP 118/76, RR 18, SpO…
- USMLE Step 1 · easy16. A 3-year-old boy from West Africa presents with hepatosplenomegaly, jaundice, and severe anemia (hemoglobin 6.2 g/dL). Vital signs show temperature 38.9°C, heart rate 128/min, b…
- USMLE Step 1 · medium17. A 6-year-old boy presents with a pruritic rash on exposed skin areas after playing in a grassy field. Vital signs are normal (BP 95/60, HR 98, RR 20, Temp 37.2°C, SpO2 98%). Lin…
- USMLE Step 1 · medium18. A 28-year-old man from the Mississippi River valley presents with fever, cough, and progressive pulmonary infiltrates. Blood cultures and sputum cultures grow a dimorphic fungus…
- USMLE Step 1 · easy19. A 34-year-old woman with HIV/AIDS (CD4 count 85 cells/μL) presents with progressive dyspnea, fever, and dry cough for 3 weeks. Vital signs show temperature 38.5°C, heart rate 10…
- USMLE Step 1 · hard20. A 52-year-old construction worker from Brazil with no immunosuppression presents with progressive nodules on the lips, gums, and tongue featuring central suppuration and satelli…
- USMLE Step 1 · easy21. A 41-year-old HIV-positive man with CD4 count of 85 cells/μL presents with fever (38.9°C), headache, and neck stiffness for 2 weeks. Vital signs show BP 110/70 mmHg, HR 98/min,…
- USMLE Step 1 · medium22. A 28-year-old male gardener presents with a 3-week history of progressive linear nodules and draining ulcers along his forearm following a rose thorn puncture injury. Vital sign…
- USMLE Step 1 · hard23. A 38-year-old woman who works in a leather factory in Venezuela presents with a painless nodule on her arm that has progressed over 6 months to multiple warty plaques with a "ca…
- USMLE Step 1 · medium24. A 62-year-old man with poorly controlled diabetes (HbA1c 11.2%) presents with fever (38.9°C), tachycardia (HR 108), and black necrotic tissue involving the hard palate and sinus…