Mycology/Parasitology USMLE Step 1 Practice Question
A 62-year-old man with poorly controlled diabetes (HbA1c 11.2%) presents with fever (38.9°C), tachycardia (HR 108), and black necrotic tissue involving the hard palate and sinuses with rapidly progressive cellulitis. Blood cultures remain negative. CT imaging shows invasive sinusitis with palatal necrosis. Histopathology demonstrates broad, nonseptate hyphae with angioinvasion and tissue infarction. He denies recent antibiotics. Which of the following is the most likely diagnosis?
Answer choices
- ACoccidioidomycosis
- BCandidemia
- CCryptococcosis
- DMucormycosisCorrect answer
- EAspergillosis
- FBlastomycosis
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