Lipid Biochemistry USMLE Step 1 Practice Questions
102 board-style USMLE Step 1 questions in Biochemistry. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard1. A 34-year-old man with a history of recurrent acute pancreatitis presents with triglycerides of 450 mg/dL and total cholesterol of 280 mg/dL. His LDL is 140 mg/dL and HDL is 25…
- USMLE Step 1 · medium2. A 52-year-old woman presents with xanthomas on her eyelids and Achilles tendons, along with premature coronary artery disease. Laboratory studies show LDL cholesterol of 420 mg/…
- USMLE Step 1 · hard3. A 3-year-old child presents with failure to thrive, hepatosplenomegaly, and a pathologic femur fracture. Vital signs show HR 110/min, RR 28/min, temperature 37.2°C. Laboratory s…
- USMLE Step 1 · medium4. A 45-year-old man with diabetes mellitus type 2 presents with recurrent pancreatitis. Laboratory studies show triglycerides of 1,200 mg/dL and total cholesterol of 680 mg/dL. Hi…
- USMLE Step 1 · medium5. A 6-year-old boy presents with severe growth retardation, steatorrhea, and progressive neurodegeneration. Vital signs show BP 95/60, HR 102, RR 20, temperature 37.2°C, and SpO2…
- USMLE Step 1 · hard6. A 42-year-old man presents with orange discoloration of his palms and soles, eruptive xanthomas, and laboratory findings of total cholesterol 320 mg/dL, triglycerides 180 mg/dL,…
- USMLE Step 1 · hard7. A 64-year-old man with prior myocardial infarction presents with hypertension (BP 152/88 mmHg), heart rate 82 bpm, and denies chest pain. He takes atorvastatin 80 mg daily with…
- USMLE Step 1 · hard8. A 35-year-old man with xanthomas on his Achilles tendons and corneal arcus presents with chest pain. Vital signs: BP 165/95 mmHg, HR 92/min, RR 16/min, Temp 37°C. Labs reveal LD…
- USMLE Step 1 · medium9. A 45-year-old man with a history of recurrent acute pancreatitis presents with eruptive xanthomas on his extensor surfaces. Vital signs show BP 138/82 mmHg, HR 88/min, RR 16/min…
- USMLE Step 1 · medium10. A 62-year-old woman undergoing chemotherapy for breast cancer presents with acute dyspnea and pleuritic chest pain. Vital signs show BP 138/82, HR 102, RR 22, temp 37.8°C, SpO2…
- USMLE Step 1 · medium11. A 56-year-old man with a 20-year history of poorly controlled diabetes presents with lipemic plasma and eruptive xanthomas. His total cholesterol is 380 mg/dL, triglycerides are…
- USMLE Step 1 · hard12. A 19-year-old college student presents with acute onset of severe headache, neck stiffness, and petechial rash. Vital signs show temperature 39.2°C, HR 118/min, BP 102/68 mmHg,…
- USMLE Step 1 · hard13. A 41-year-old woman presents for routine lipid screening. Vital signs are normal (BP 118/76, HR 72, RR 14). Fasting labs show HDL 65 mg/dL, triglycerides 95 mg/dL, and LDL calcu…
- USMLE Step 1 · hard14. A 28-year-old man presents with recurrent pancreatitis and is found to have fasting triglycerides of 800 mg/dL and total cholesterol of 350 mg/dL. Vital signs show BP 128/82 mmH…
- USMLE Step 1 · medium15. A 35-year-old woman on atorvastatin 40 mg daily presents with acute myalgia, proximal weakness, and dark urine. Vital signs: BP 128/82, HR 92, RR 16, Temp 37.2°C, SpO2 98%. Labo…
- USMLE Step 1 · medium16. A 3-year-old boy presents with failure to thrive, hepatosplenomegaly, and developmental delay. Vital signs show HR 102/min, RR 24/min, temp 37.8°C. Laboratory analysis reveals t…
- USMLE Step 1 · medium17. A 45-year-old man presents with xanthomas on his Achilles tendons and eyelids, along with corneal arcus. Laboratory studies show total cholesterol of 650 mg/dL and LDL of 520 mg…
- USMLE Step 1 · medium18. A 19-year-old female with consanguineous parents presents with orbital and eruptive xanthomas on the buttocks. Vital signs: BP 118/76, HR 88, RR 16, Temp 37°C, SpO2 98%. Serum t…
- USMLE Step 1 · hard19. A 48-year-old woman presents with progressive memory loss, peripheral neuropathy, and ataxia. Vital signs are stable (BP 118/76, HR 72, RR 14, Temp 37°C). MRI demonstrates cereb…
- USMLE Step 1 · medium20. A 7-year-old boy presents with growth retardation, chronic diarrhea, and steatorrhea. Vital signs show weight 15th percentile for age. Laboratory studies reveal fat-soluble vita…
- USMLE Step 1 · hard21. A 68-year-old man with longstanding type 2 diabetes (BP 148/92, HR 88, on atorvastatin 80 mg daily) presents with advanced atherosclerosis. Current labs show LDL cholesterol 95…
- USMLE Step 1 · medium22. A 55-year-old man with metabolic syndrome presents with BP 148/92 mmHg, HR 88/min, and fasting labs showing triglycerides 450 mg/dL, HDL 32 mg/dL, glucose 118 mg/dL, and elevate…
- USMLE Step 1 · easy23. A 61-year-old woman with hyperlipidemia presents with corneal opacities and tendon xanthomas. Her lipid panel shows total cholesterol 520 mg/dL, LDL 380 mg/dL, and HDL 45 mg/dL.…
- USMLE Step 1 · hard24. A 38-year-old man presents with recurrent myocardial infarction despite atorvastatin 80 mg daily and normal LDL cholesterol of 95 mg/dL. Vital signs: BP 138/88 mmHg, HR 92 bpm,…