Inflammation and Immune Pathology USMLE Step 1 Practice Questions
54 board-style USMLE Step 1 questions in Pathology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 Ā· medium25. A 32-year-old woman with a 3-year history of systemic lupus erythematosus presents to the emergency department with acute onset dyspnea, pleuritic chest pain, and low-grade feveā¦
- USMLE Step 1 Ā· medium26. A 45-year-old woman presents with joint pain, morning stiffness lasting 2 hours, and swelling in her hands and feet bilaterally. Laboratory studies show elevated rheumatoid factā¦
- USMLE Step 1 Ā· medium27. A 28-year-old woman with systemic sclerosis presents with severe Raynaud's phenomenon, finger ulceration, and progressive skin tightening. Vital signs: BP 142/88, HR 98, RR 16,ā¦
- USMLE Step 1 Ā· hard28. A 68-year-old woman presents to rheumatology clinic with a 4-month history of symmetric polyarticular pain and swelling affecting her hands, wrists, and knees. She reports morniā¦
- USMLE Step 1 Ā· hard29. A 22-year-old male presents to the emergency department with a 3-day history of severe colicky abdominal pain and bloody diarrhea that began 3 days after an upper respiratory inā¦
- USMLE Step 1 Ā· medium30. A 34-year-old woman presents with fever (38.5Ā°C), polyarthralgias, and a photosensitive malar rash. Vital signs show BP 128/82 mmHg, HR 92/min, RR 16/min, SpO2 98% on room air.ā¦
- USMLE Step 1 Ā· medium31. A 55-year-old male with a 30 pack-year smoking history presents with a 3-month history of progressive dyspnea and dry cough. He denies fever, night sweats, or weight loss. Vitalā¦
- USMLE Step 1 Ā· hard32. A 38-year-old man with no prior skin conditions presents with erythematous, scaly patches on his elbows and knees. Vital signs: BP 128/82, HR 88, RR 16, Temp 37.2Ā°C. Removing scā¦
- USMLE Step 1 Ā· hard33. A 19-year-old male college student presents to the emergency department with a 12-hour history of fever (39.2Ā°C), severe pharyngitis, and a rapidly progressive petechial rash beā¦
- USMLE Step 1 Ā· hard34. A 55-year-old woman presents with diffuse maculopapular rash, fever (38.9Ā°C), and cervical lymphadenopathy 1 week after initiating phenytoin for seizure prophylaxis. Vital signsā¦
- USMLE Step 1 Ā· medium35. A 3-year-old boy presents with recurrent pyogenic infections caused by Staphylococcus aureus and Streptococcus pneumoniae. On examination, he has a chronic boil on his arm (BP 9ā¦
- USMLE Step 1 Ā· medium36. A 6-year-old boy presents to the emergency department with epistaxis and diffuse petechiae on his lower extremities and trunk. His mother reports he had an upper respiratory infā¦
- USMLE Step 1 Ā· easy37. A 28-year-old woman with documented penicillin allergy develops sudden-onset dyspnea, chest pain, and urticaria 2 hours after receiving penicillin for streptococcal pharyngitis.ā¦
- USMLE Step 1 Ā· medium38. A 34-year-old woman presents with sudden-onset polyarthralgias, fever, and a painful erythematous rash on her lower extremities. Vital signs show temperature 38.5Ā°C, heart rateā¦
- USMLE Step 1 Ā· hard39. A 52-year-old woman with severe rheumatoid arthritis started on infliximab two months ago presents with productive cough, fever (38.9Ā°C), and weight loss. Vital signs show HR 10ā¦
- USMLE Step 1 Ā· medium40. A 72-year-old woman presents with severe bilateral temporal headache and jaw claudication. Vital signs show BP 148/92 mmHg, HR 88/min, RR 16/min, temp 37.8Ā°C. Laboratory studiesā¦
- USMLE Step 1 Ā· medium41. A 67-year-old man with cellulitis of the right lower extremity presents with fever (39.4Ā°C), tachycardia (102 bpm), and tachypnea (18 breaths/min). Blood cultures are pending; Wā¦
- USMLE Step 1 Ā· medium42. A 55-year-old woman presents with community-acquired pneumonia. Vital signs show temperature 39.2Ā°C, heart rate 112 bpm, respiratory rate 24/min, blood pressure 128/82 mmHg, andā¦
- USMLE Step 1 Ā· medium43. A 6-year-old boy presents with recurrent pyogenic infections and progressive neurologic decline. Vital signs show HR 102 bpm, RR 24/min, BP 98/62 mmHg, temperature 37.2Ā°C. He exā¦
- USMLE Step 1 Ā· medium44. A 29-year-old woman presents with recurrent oral thrush despite otherwise normal health. Vital signs are stable (BP 118/76, HR 82, RR 16, Temp 37.2Ā°C, SpO2 98%). Laboratory evalā¦
- USMLE Step 1 Ā· medium45. A 4-year-old boy presents with recurrent skin abscesses and pneumonias caused by catalase-positive organisms. Vital signs show HR 102/min, RR 24/min, temperature 38.2Ā°C, BP 95/6ā¦
- USMLE Step 1 Ā· medium46. A 38-year-old woman presents with acute right lower quadrant pain, fever (38.9Ā°C), tachycardia (102 bpm), and tachypnea (18 breaths/min). Physical examination reveals rebound teā¦
- USMLE Step 1 Ā· medium47. A 51-year-old man presents with acute bacterial pneumonia, fever (39.2Ā°C), tachycardia (102 bpm), tachypnea (24/min), and hypoxia (SpO2 88% on room air). Chest X-ray shows consoā¦
- USMLE Step 1 Ā· medium48. A 3-year-old girl presents with recurrent pyogenic infections and hepatosplenomegaly. Vital signs show HR 110/min, RR 28/min, BP 95/60 mmHg, temperature 37.8Ā°C. Laboratory studiā¦