Coronary Artery Disease USMLE Step 1 Practice Questions
55 board-style USMLE Step 1 questions in Cardiovascular. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · easy1. A 42-year-old woman presents for routine health maintenance. She reports no current symptoms and denies chest pain, dyspnea, or claudication. She works as an accountant and exer…
- USMLE Step 1 · hard2. A 45-year-old man with familial hypercholesterolemia (LDL 280 mg/dL despite statin therapy) presents with acute ST-elevation myocardial infarction. He is taken urgently for PCI.…
- USMLE Step 1 · medium3. A 68-year-old man with a 5-year history of stable angina presents for evaluation of chest pain that occurs with exertion and is relieved by rest. His symptoms are well-controlle…
- USMLE Step 1 · hard4. A 48-year-old woman with hypercholesterolemia and no other cardiac risk factors presents to the emergency department with acute-onset severe substernal chest pain and dyspnea. V…
- USMLE Step 1 · medium5. A 70-year-old man with a history of myocardial infarction 2 years ago and stage 3b chronic kidney disease (serum creatinine 2.8 mg/dL, eGFR 22 mL/min/1.73m²) presents with 3 mon…
- USMLE Step 1 · medium6. A 55-year-old woman with a 10-year history of type 2 diabetes mellitus and hyperlipidemia (LDL 156 mg/dL despite atorvastatin) presents to the emergency department with acute su…
- USMLE Step 1 · easy7. A 62-year-old man with a 40-pack-year smoking history presents with substernal chest pain that began 6 hours ago while mowing his lawn. The pain radiates to his left arm and is…
- USMLE Step 1 · medium8. A 61-year-old man with a history of anterior wall myocardial infarction 8 months ago presents with recurrent angina despite optimal medical therapy with aspirin 81 mg daily, ato…
- USMLE Step 1 · medium9. A 52-year-old woman with hypertension presents to the emergency department with a 6-week history of progressive dyspnea, orthopnea, and fatigue. She denies chest pain, has no sm…
- USMLE Step 1 · hard10. A 58-year-old man with a history of hypertension and hyperlipidemia presents to the emergency department with 3 hours of acute-onset substernal chest pain radiating to his left…
- USMLE Step 1 · medium11. A 70-year-old man with known CAD and prior stent placement 5 years ago presents with recurrent angina. Stress testing shows inducible ischemia. Angiography reveals 85% stenosis…
- USMLE Step 1 · easy12. A 48-year-old man with a 10-year history of hypertension and hyperlipidemia presents to the emergency department with acute substernal chest pain that began 90 minutes ago. The…
- USMLE Step 1 · medium13. A 37 year old woman develops sudden left arm weakness shortly after a long airplane flight. Duplex ultrasound of the leg reveals a deep venous thrombosis. Transthoracic echocard…
- USMLE Step 1 · medium14. A 34-year-old male heavy smoker presents with severe pain in his fingers and toes. Vital signs show BP 118/76, HR 92, RR 16, temp 37°C, SpO2 98%. Examination reveals distal extr…
- USMLE Step 1 · easy15. A 66-year-old man with type 2 diabetes and 40 pack-year smoking history presents with cramping calf pain after walking two blocks that resolves with rest. Vital signs: BP 158/92…
- USMLE Step 1 · easy16. A 47-year-old woman returns from a 12-hour international flight and develops acute left calf pain, swelling, and warmth. Vital signs: BP 132/84 mmHg, HR 98 bpm, RR 18, temp 37.2…
- USMLE Step 1 · medium17. A 76-year-old woman with hypertension presents with repeated episodes of lightheadedness and intermittent palpitations followed by prolonged pauses. Vital signs show BP 142/88 m…
- USMLE Step 1 · hard18. A 25-year-old healthy volunteer participates in a cardiac physiology experiment and receives an intravenous infusion of a beta-1 agonist. Vital signs show HR 98 bpm, BP 128/76 m…
- USMLE Step 1 · hard19. A 68-year-old man presents with acute substernal chest pain radiating to his left arm for 2 hours. Vital signs: BP 142/88 mmHg, HR 102 bpm, RR 20, temp 37.2°C, SpO2 98% on room…
- USMLE Step 1 · medium20. A 72-year-old man with chronic uncontrolled hypertension (BP 168/98 mmHg, HR 88/min, RR 16/min) presents with exertional chest discomfort. Physical examination reveals a promine…
- USMLE Step 1 · hard21. A 57-year-old woman with myxomatous mitral valve degeneration presents with dyspnea on exertion. Vital signs show BP 138/72 mmHg, HR 88/min, RR 18/min, SpO2 98% on room air. Ech…
- USMLE Step 1 · hard22. A 62-year-old man with hypertension presents with chest pain and dyspnea on exertion. Vital signs show BP 158/92 mmHg, HR 88 bpm, RR 18/min, SpO2 98% on room air. ECG demonstrat…
- USMLE Step 1 · medium23. A 49-year-old man with Marfan syndrome presents with progressive exertional dyspnea. Vital signs show BP 160/45 mmHg, HR 92 bpm, RR 18, and SpO2 98% on room air. Physical examin…
- USMLE Step 1 · easy24. A 3-month-old male presents with poor feeding and a harsh holosystolic murmur best heard at the left lower sternal border. Vital signs show HR 145 bpm, RR 42/min, BP 92/58 mmHg,…