Coagulation Disorders USMLE Step 1 Practice Questions
55 board-style USMLE Step 1 questions in Hematology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium25. A 45-year-old man with cirrhosis presents with epistaxis and easy bruising. Vital signs: BP 128/76, HR 92, RR 16, Temp 37°C, SpO2 98%. He denies recent anticoagulant use. Labora…
- USMLE Step 1 · hard26. A 32-year-old woman with no past medical history presents with severe abdominal pain, watery diarrhea, and confusion. Vital signs show BP 158/94 mmHg, HR 102/min, RR 20/min, Tem…
- USMLE Step 1 · medium27. A 9-year-old boy is brought to the pediatric clinic by his mother for evaluation of recurrent nosebleeds and easy bruising over the past 2 years. His maternal grandmother and mo…
- USMLE Step 1 · medium28. A 45-year-old man with cirrhosis secondary to hepatitis C presents to the emergency department after experiencing prolonged bleeding from a dental extraction 2 days ago. He repo…
- USMLE Step 1 · medium29. A 28-year-old woman with no significant past medical history presents to the emergency department with spontaneous gingival bleeding and a petechial rash on her lower extremitie…
- USMLE Step 1 · medium30. A 68-year-old man with newly diagnosed gastric cancer presents with acute-onset bilateral lower extremity pain and swelling. Vital signs show BP 138/82, HR 92, RR 18, temp 37.2°…
- USMLE Step 1 · easy31. A 6-month-old boy is brought to the emergency department after prolonged bleeding from his circumcision site 3 hours ago. The bleeding has not stopped despite direct pressure fo…
- USMLE Step 1 · medium32. A 3-year-old boy is brought to the emergency department with a 2-day history of fever (38.5°C), petechial rash, and lethargy. His parents report he was in his usual state of hea…
- USMLE Step 1 · medium33. A 68-year-old man on broad-spectrum antibiotics for severe pneumonia develops gingival bleeding and prolonged oozing from venipuncture sites. Vital signs: BP 128/76, HR 92, RR 1…
- USMLE Step 1 · medium34. A 30-year-old woman with three recurrent first-trimester miscarriages presents with left leg swelling and pain. Vital signs show BP 118/76, HR 92, RR 16, Temp 37°C, SpO2 98%. Du…
- USMLE Step 1 · medium35. A 47-year-old man with recurrent deep venous thromboses is started on warfarin monotherapy without bridging heparin. Two days later, he develops painful purpuric skin lesions on…
- USMLE Step 1 · medium36. A 31 year old woman presents with unilateral leg swelling 2 weeks after starting an estrogen containing oral contraceptive. Her mother had multiple deep venous thromboses. Coagu…
- USMLE Step 1 · medium37. A 66-year-old man hospitalized for pulmonary embolism is started on intravenous unfractionated heparin. On hospital day 6, he develops right leg pain and swelling. Vital signs s…
- USMLE Step 1 · medium38. A 26-year-old woman presents with petechiae and easy bruising two weeks after a viral upper respiratory infection. Vital signs are stable (BP 118/76, HR 82, RR 16, Temp 37°C). P…
- USMLE Step 1 · medium39. A 14-year-old girl presents to her primary care physician with a 6-month history of progressively heavy menstrual periods requiring frequent pad changes and soaking through over…
- USMLE Step 1 · hard40. A 12 year old boy is evaluated for recurrent epistaxis and excessive bleeding after minor cuts. Laboratory studies show thrombocytopenia and prolonged bleeding time. Platelet ag…
- USMLE Step 1 · medium41. A 19-year-old woman presents with lifelong menorrhagia requiring frequent transfusions and recurrent epistaxis. She reports prolonged bleeding for 3 hours after dental extractio…
- USMLE Step 1 · easy42. A 7 year old boy is brought for recurrent painful swelling of the knees and elbows after minor trauma. His maternal uncle had a similar disorder. Laboratory studies show normal…
- USMLE Step 1 · hard43. A 35-year-old woman presents with confusion, fever, and dark urine. Vital signs show temperature 38.9°C, blood pressure 108/72 mmHg, heart rate 102/min, respirations 18/min, and…
- USMLE Step 1 · medium44. A 32 year old woman develops profuse vaginal bleeding shortly after placental abruption. She has oozing from intravenous catheter sites. Laboratory studies show platelets 42,000…
- USMLE Step 1 · easy45. A 29-year-old Rh-negative woman delivers her second child vaginally. She had elevated anti-D antibodies during pregnancy. The newborn presents with jaundice at 12 hours of life…
- USMLE Step 1 · medium46. A 43-year-old man with chemotherapy-induced thrombocytopenia receives a platelet transfusion. Thirty minutes later, he develops fever (38.9°C), chills, and malaise. Vital signs…
- USMLE Step 1 · medium47. A 52-year-old woman with a history of iron deficiency anemia receives a packed red blood cell transfusion for gastrointestinal bleeding. Minutes into the transfusion, she develo…
- USMLE Step 1 · medium48. A 63-year-old man is recovering after hip replacement surgery and has been receiving unfractionated heparin. On hospital day 6 he develops pain and swelling in the left calf. La…