Coagulation Disorders USMLE Step 1 Practice Questions
55 board-style USMLE Step 1 questions in Hematology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard1. An investigator is conducting a phase 1 trial for a novel epoxide reductase inhibitor with favorable pharmacokinetic properties for cerebrovascular accident prophylaxis. Two day…
- USMLE Step 1 · hard2. An investigator is conducting a phase 1 trial for a novel epoxide reductase inhibitor with favorable pharmacokinetic properties for cerebrovascular accident prophylaxis. Two day…
- USMLE Step 1 · hard3. A 28-year-old woman presents to the hematology clinic for evaluation of recurrent thromboembolism. She has a history of two unprovoked deep vein thromboses at ages 24 and 26, an…
- USMLE Step 1 · medium4. A 72-year-old man with a history of atrial fibrillation has been taking warfarin for 18 months with a stable INR of 2.8–3.2. He presents to the emergency department with gross h…
- USMLE Step 1 · medium5. A 34-year-old woman presents to the emergency department with severe vaginal bleeding and easy bruising. Laboratory studies show PT 18 seconds (normal 11-13), aPTT 45 seconds (n…
- USMLE Step 1 · hard6. A 34-year-old woman who is 28 weeks pregnant presents with severe headache, visual disturbances, and right upper quadrant pain. Laboratory studies show platelet count 45,000/μL,…
- USMLE Step 1 · hard7. A 19-year-old previously healthy man presents with acute bilateral leg pain, cyanosis of his feet, and gangrene developing within hours. Laboratory studies show a platelet count…
- USMLE Step 1 · hard8. A 45-year-old man with hemophilia A is scheduled for elective total abdominal colectomy for adenocarcinoma. He has a baseline factor VIII activity of 12% and reports good compli…
- USMLE Step 1 · hard9. A 62-year-old woman with newly diagnosed adenocarcinoma of the lung completed her second cycle of chemotherapy 2 weeks ago. She presents to the emergency department with acute d…
- USMLE Step 1 · easy10. A 6-year-old boy with a family history of bleeding disorders presents with epistaxis and excessive bleeding after a minor laceration to his lip. Laboratory studies reveal a norm…
- USMLE Step 1 · medium11. A 28-year-old man with no significant past medical history presents with spontaneous bleeding from the gums, blood in the stool, and a petechial rash. His laboratory results sho…
- USMLE Step 1 · medium12. A 35-year-old woman with a history of three miscarriages presents with a deep vein thrombosis in the right lower extremity. Physical examination reveals livedo reticularis on he…
- USMLE Step 1 · hard13. A 3-year-old boy presents with a 6-month history of spontaneous hemarthrosis, intramuscular hematomas, and epistaxis. His mother reports no significant bleeding history. Laborat…
- USMLE Step 1 · hard14. A 41-year-old woman presents for preoperative clearance prior to elective hysterectomy. She reports no personal or family history of bleeding disorders. On review of systems, sh…
- USMLE Step 1 · easy15. A 19-year-old previously healthy male presents to the emergency department with severe bleeding from the gums and diffuse petechiae on his lower extremities. Two hours prior, he…
- USMLE Step 1 · hard16. A 28-year-old woman presents to the emergency department with acute abdominal pain and leg swelling. She reports two unexplained pregnancy losses in the past year and was hospit…
- USMLE Step 1 · easy17. A 6-year-old boy presents to the emergency department with spontaneous hemarthrosis of the left knee and ecchymoses on his arms and legs following minor trauma 2 days ago. His m…
- USMLE Step 1 · hard18. A 45-year-old woman undergoes preoperative screening before elective surgery. Laboratory studies reveal elevated aPTT (48 seconds) with normal PT (12 seconds), platelet count (2…
- USMLE Step 1 · medium19. A 68-year-old man with metastatic pancreatic cancer presents to the emergency department with acute onset bilateral leg swelling, dyspnea, and right-sided chest pain. Vital sign…
- USMLE Step 1 · medium20. A 52-year-old man with a 10-year history of alcohol use disorder and biopsy-proven cirrhosis presents to the emergency department with hematemesis. Physical examination reveals…
- USMLE Step 1 · medium21. A 34-year-old woman presents to her primary care physician with a 20-year history of heavy menstrual bleeding requiring iron supplementation and occasional transfusion. She repo…
- USMLE Step 1 · easy22. A 3-year-old boy is brought to the emergency department by his mother after spontaneous epistaxis lasting 2 hours. She reports he had prolonged bleeding for 5 days following cir…
- USMLE Step 1 · hard23. A 16-year-old boy with hemophilia A has been on prophylactic factor VIII therapy (20 units/kg IV twice weekly) for the past 8 years. He presents to the emergency department with…
- USMLE Step 1 · hard24. A 28-year-old man presents with acute left leg pain and swelling. Vital signs: BP 118/76, HR 92, RR 16, temp 37°C, SpO2 98% on room air. Duplex ultrasound confirms left femoral…